It is with great sadness we announce that Dr. Ralph T. Holman, AOCS Past President and renowned scientist has passed away at the age of 94. AOCS extends condolences to Dr. Holman’s family and to his many friends. AOCS Governing Board member and longtime friend, Dr. Douglas Bibus sent us the following message.
Dear Friends and Colleagues,
Dr Ralph Holman passed away peacefully yesterday morning surrounded by loved ones. Ralph was an amazing scientist and an incredible person.
I was incredibly blessed by this man and enjoyed every opportunity to spend time with him. He taught me science but even more importantly how to be a person.
Even in his age, he managed to continue to smile, maintain his optimism and keep all around entertained with his quick whit. Ralph remained physically healthy until the end, requiring only a small dose of bp meds. He passed away from complications related to pneumonia. Ralph had one of the highest omega 3 levels that we have ever measured, likely due to his daily intake of sardines, fish and vegetables.
Ralph made many friends in the past few years in the nursing home. He liked to sit with women at the lunch table because they were better conversationalists! We had a dehydration event in January and the attending MD said Ralph would not leave the hospital. One week later he was walking, joking, talking and reading scripture. So many asked how could this be!
We had an amazing 94th birthday in March. Ralph continued to say, what a nice surprise. Ralph was known to walk and wheel the nursing home halls making sure everyone was ok and visiting with nurses and staff.
I have attached a copy of Ralph's obituary, his picture, a writeup by author Susan Allport, his essay entitled 'FINALE' that he wanted shared at his death. Ralph was often frustrated in the 80s and 90s that omega 3 was not more widely accepted. His paper to that effect is also attached.
A special thanks to Lola Cottew who has cared for Dr Holman daily for the past 7 years. Lola's friendship and "gift of gab" dramatically provided quality of life to Ralph who while appearing quiet, loved to chat and visit. A frequent sign on his back door said, " I am sleeping because I have no one to talk to, KNOCK HARD to wake me so we can visit!"
Additionally, Angie Hjelle, executive director of the Bethel University Foundation, made sure Ralph's affairs were handled professionally and carefully. Her frequent trips to Austin/Albert Lea were welcomed by all of us and especially by Ralph who frequently asked where the pretty Bethel lady was. Ralph often referred to us as his omega kids. Our unique experiences with Ralph have cemented life long friendships.
May we all live with the spirit and love that Dr Holman gave every day. Thank you to if you interacted with Dr Holman and/or continue to advance the science of omega 3/nutrition and the spirit of humanity.
Kind regards
Doug
Memorials are directed to Save the Children (www.savethechildren.org) who promote nutrition and health for disadvantaged children around the world or your preferred charity.
--
Obituary ~Dr. Ralph T. Holman
Dr. Ralph T. Holman, 94 of Austin,
MN, died peacefully surrounded by loved ones on Wednesday, August 15, 2012 at
Mayo Clinic Health Systems, Albert Lea.
Ralph Theodore Holman was born March
4, 1918 in Minneapolis, MN the son of Alfred T. and May (Nilson) Holman. He was
a graduate of Roosevelt High School, from Bethel College, The University of Minnesota
and Rutgers University.
Ralph married Karla Calais on March
26, 1943 at the University of Minnesota Chapel. They lived in Minneapolis prior
to moving to Sweden. Upon returning to the United States, they lived in Texas
until moving to Austin, MN in 1951.
In 1946, Dr. Holman worked at the
Karolinska Institute in Stockholm, Sweden with several Nobel Prize winners,
including Sune Berstrom. He was the first person in the world to crystalize
lipoxygenase, a significant enzyme in the inflammatory process. Following his
time in Sweden, Dr. Holman spent time as a professor at Texas A and M
University. In 1951, while a professor at the University of Minnesota in
Minneapolis, Dr. Holman was invited to join the Hormel Institute in Austin MN
which at the time was pioneering food stabilization technology. Dr. Holman
spent the entirety of his career at his beloved Hormel Institute, University of
Minnesota, finally retiring in 2001.
Professor Holman was a pioneer in
the area of essential fatty acid research and nutrition, making several
fundamental discoveries about the metabolism of fatty acids. He is perhaps best
known for coining the term "Omega 3" in 1963 which Holman said came
from his knowledge of the Bible and Sunday school from the passage "I am
the Alpha and the Omega". Dr.
Holman was a devout Christian and led his life in pursuit of goodness and
helping others.
Dr. Holman is regarded as the Father
of Omega 3 fatty acids, discovering their essential nature, their metabolism
and competition with omega 6 fatty acids and spawning many of the top lipid
researchers in the day that passed through his lab at the Hormel Institute. His science, discoveries, life and ambitions
have improved the lives of millions around the globe through nutrition.
Dr. Holman was the Director of the
Hormel Institute from 1975 to 1985 and on the Board of Directors for Hormel
Foods. He was a past president of the
American Oil Chemists Society, and received numerous awards and honors
including the Borden Award and the prestigious Baldwin Award. He was a member
of the prestigious National Academy of Sciences, an invitation-only membership,
the Royal Orchid Society, and many other scientific organizations.
His hobbies included photography and
growing numerous orchids in a greenhouse he had constructed on the back of his
home. Dr. Holman also enjoyed spending
time at his Swedish style cabin in Upsala Minnesota that he built with Karla
and young son Ted.
Dr. Holman was preceded in death by
his parents and his loving wife, Karla.
Ralph is survived by his son Nils
(Ted) Holman, Minneapolis, MN; nieces, nephews and cousins.
Publications of Ralph T. Holman
Updated 22oct96
1. Ralph T. Holman, M. Wight Taylor and
Walter C. Russell. The Sulfur Balance of
the Non-Laying, Molting and Laying Hen.
J. Nutr. 29, 277-281 (1945).
(Master's Thesis).
2. Ralph T. Holman, Walter O. Lundberg,
Walter M. Lauer and George O. Burr.
Spectrophotometric Studies of the Oxidation of Fats. I.
Oleic Acid, Ethyl Oleate and Elaidic Acid. J. Am. Chem. Soc. 67, 1285-1292 (1945) (Ph.D. Thesis).
3. Ralph T. Holman, Walter O. Lundberg and
George O. Burr. Spectrophotometric
Studies of the Oxidation of Fats. II.
The Oxidation of Dienoic Fatty Acids. J.
Am. Chem. Soc. 67, 1386-1390 (1945). (Ph.D. Thesis).
4. Ralph T. Holman, Walter O. Lundberg and
George O. Burr. Spectrophotometric
Studies of the Oxidation of Fats.
III. Ultraviolet Absorption
Spectra of Oxidized Octadecatrienoic Acids.
J. Am. Chem. Soc. 67, 1390-1394
(1945). (Ph.D. Thesis).
5. Ralph T. Holman and George O. Burr. Spectrophotometric Studies of Fats. IV.
Ultraviolet Absorption Spectra of Lipoxidase-Oxidized Fats. Arch. Biochem. 37,
47-54 (1945).
6. Ralph T. Holman, Walter O. Lundberg and
George O. Burr. Spectrophotometric
Studies of the Oxidation of Fats.
V. The Color of Oxidized Fats in
Alcoholic Alkali. J. Am. Chem. Soc. 67, 1669-1672 (1945).
7. Ralph T. Holman and George O. Burr. Spectrophotometric Studies of the Oxidation
of Fats. VI. Oxygen Absorption and Chromophore Production
in Fatty Esters. J. Am. Chem. Soc. 68, 562-566 (1946).
8. Ralph T. Holman. Spectrophotometric Studies of the Oxidation
of Fats. VII. Oxygen Absorption and Chromophore Production
in Lipoxidase-Oxidized Fatty
Esters. Arch. Biochem. 10, 519-529 (1946).
9. Ralph T. Holman. Spectrophotometric Studies of the Oxidation
of Fats. VIII. Coupled Oxidation of
Carotene. Arch. Biochem. 21, 51-57 (1949).
10. Ralph T. Holman. Spectrophotometric Studies of the Oxidation
of Fats. IX. Coupled Oxidation of
Vitamin A Acetate. Arch. Biochem. 26, 85-91 (1950).
11. W. O. Lundberg, R. T. Holman and G. O.
Burr. Spectroscopic Changes in Fats
During Rancidification. Oil & Soap 23, 10-14 (1946).
12. W. O. Lundberg, R. T. Holman and G. O.
Burr. Deterioration of Fats and Oils.
Quartermaster Corps Manual 17-7, p. 27 (1945).
13. Irving I. Rusoff, Ralph T. Holman and
George O. Burr. A Table of Spectroscopic
Data on Fats, Fatty Acids, and Their Esters.
Oil & Soap 22, 290-294 (1945).
14. Norman Kretchmer, Ralph T. Holman and
George O. Burr. A Submicro Method for
the Determination of Iodine Number of Lipids.
Arch. Biochem. 10, 101-105 (1946).
15. Otto C. Elmer and Ralph T. Holman. Preparation of Linoleic and Linolenic Acid
Esters of Several Poly-Hydroxy Alcohols.
Off. Dig., Fed. Paint Varn. Prod. Clubs 263,
711-716 (1946).
16. Ralph T. Holman and Otto C. Elmer. The Rates of Oxidation of Unsaturated Fatty
Acids and Esters. J. Am. Oil Chem. Soc. 24, 127-129 (1947).
17. Hugo Theorell, Ralph T. Holman and Ake
Akeson. A Note on the Preparation of Crystalline
Soy Bean Lipoxidase. Arch. Biochem. 14, 250-252 (1947).
18. Hugo Theorell, Ralph T. Holman and Ake
Akeson. Crystalline Lipoxidase. Acta
Chem. Scand. 1, 571-576 (1947).
19. Ralph Theodore Holman. Crystalline Lipoxidase. II.
Lipoxidase Activity. Arch. Biochem. 15,
403-413 (1947).
20. Ralph T. Holman, Frances Panzer, B. S.
Schweigert and Stanley R. Ames. Crystalline Lipoxidase. III.
Amino Acid Composition. Arch.
Biochem. 26, 199-204 (1950).
21. Ralph T. Holman and George O. Burr. Alkali Conjugation of the Unsaturated Fatty
Acids. Arch. Biochem. 19, 474-482 (1948).
21a. Irma Rieckehoff, Ralph Holman and George
Burr. Effect of Diet on Polyethenoid
Fatty Acids of Rat Tissues. Fed. Proc. 6, No. 1, Mar. (1947). (Abstract)
22. Irma G. Rieckehoff, Ralph T. Holman and G.
O. Burr. Polyethenoid Fatty Acid
Metabolism. Effect of Dietary Fat on
Polyethenoid Fatty Acids of Rat Tissues.
Arch. Biochem. 20, 331-340 (1949).
23. Carl Widmer, Jr. and Ralph T. Holman. Polyethenoid Fatty Acid Metabolism. II. Deposition of Polyunsaturated Fatty Acids in
Fat-Deficient Rats Upon Single Fatty Acid Supplementation. Arch. Biochem. 25,
1-12 (1950).
24. Ralph T. Holman and Thomas S. Taylor. Polyethenoid Fatty Acid Metabolism. III.
Arachidonate Supplementation. Arch.
Biochem. 29, 295-301 (1950).
25. Patrick W. Witten and Ralph T.
Holman. Polyethenoid Fatty Acid
Metabolism. V. Prooxidant-Antioxidant
Effect. Arch. Biochem. Biophys. 37, 90-98 (1952).
26. Patrick W. Witten and Ralph T.
Holman. Polyethenoid Fatty Acid
Metabolism. VI. Effect of Pyridoxine on Essential Fatty Acid Conversions. Arch. Biochem. Biophys. 41, 266-273 (1952).
27. Ralph T. Holman and Sheldon I.
Greenberg. Polyethenoid Fatty Acid
Metabolism. VII. Effect of Oxidized Linoleate
Preparations. Arch. Biochem. Biophys. 49, 49-57 (1954).
28. O. S. Privett, F. J. Pusch and Ralph T.
Holman. Polyethenoid Fatty Acid
Metabolism. VIII. Nonpotency of cis-9,trans-12-Linoleate as Essential Fatty
Acid. Arch. Biochem. Biophys. 57, 156-162 (1955).
29. Sune Bergstrom and Ralph T. Holman. Total Conjugation of Linoleic Acid in
Oxidation with Lipoxidase. Nature 161, 55-56 (1948).
30. Sune Bergstrom and Ralph T. Holman. Lipoxidase and the Autoxidation of
Unsaturated Fatty Acids. Adv. Enzymol. 8, 425-457 (1948).
31. Ralph Theodore Holman. Lipoxidase Activity and Fat Composition of
Germinating Soy Beans. Arch. Biochem. 17, 459-466 (1948).
32. V. Lorraine Schneider, Ralph T. Holman and
George O. Burr. A Monolayer Study of the
Isomerism of Unsaturated and Oxy Fatty Acids.
J. Phys. Colloid Chem. 53, 1016-1029
(1949).
33. Ralph T. Holman. Mechanism of Action of Lipoxidase. Transactions of the Third Conference on
Biological Antioxidants, Josiah Macy Jr. Foundation, p. 131 (1948).
34. Ralph T. Holman. Spectrophotometric Studies of the Oxidation
of Linoleates. Transactions of the First
Conference on Biological Antioxidants, Josiah Macy Jr. Foundation, pp. 37-41
(1946).
35. Ralph T. Holman and Lennart Hagdahl. Displacement Analysis of Lipides. Preliminary
Studies with Normal Saturated Fatty Acids.
Arch. Biochem 17, 301-310 (1948).
36. Lennart Hagdahl and Ralph T. Holman. Displacement Analysis of Lipids. II. Increased Separability of Fatty Acids by
Depressed Solubility. J. Am. Chem. Soc. 72,
701-705 (1950).
37. Ralph T. Holman and Lennart Hagdahl. Displacement Analysis of Lipides. III.
Separation of Normal Saturated Fatty Acids from Formic to Behenic. J. Biol. Chem. 182,
421-427 (1950).
38. Ralph T. Holman. Displacement Analysis of Lipids. IV.
Carrier Displacement Separation of Saturated Fatty Acids. J. Am. Chem. Soc. 73, 1261-1263 (1951).
39. Ralph T. Holman. Displacement Analysis of Lipids. V.
Separation of Substances Analogous to Fatty Acids. J. Am. Chem. Soc. 73, 3337-3340 (1951).
40. Ralph T. Holman and William T.
Williams. Displacement Analysis of
Lipids. VI. Separation of Unsaturated
Acids. J. Am. Chem. Soc. 73, 5285-5289 (1951).
41. Ralph T. Holman. Displacement Analysis of Lipids. VII. Carrier
Separation of Unsaturated Fatty Acids.
J. Am. Chem. Soc. 73, 5289-5292
(1951).
42. James G. Hamilton, Jr. and Ralph T.
Holman. Displacement Analysis of
Lipides. VIII. Preliminary Studies with
Steroids. Arch. Biochem. Biophys. 36, 456-461 (1952).
43. N. A. Khan, W. O. Lundberg and Ralph T.
Holman. Displacement Analysis of
Lipids. IX. Products of the Oxidation of Methyl
Linoleate. J. Am. Chem. Soc. 76, 1779-1784 (1954).
44. James G. Hamilton and Ralph T.
Holman. Displacement Analysis of
Lipids. X. Model Mixtures of
Glycerides. J. Am. Chem. Soc. 76, 4107-4109 (1954).
45. Ralph T. Holman. Crossing Over. A New Technique in
Displacement Analysis with the Tiselius-Claesson Interferometer. Anal. Chem. 22,
832-833 (1950).
46. Ralph T. Holman and Lennart Hagdahl. Tiselius-Claesson Interferometric Adsorption
Analysis Apparatus. Improvements in Design and Use. Anal. Chem. 23,
794-797 (1951).
47. Ralph T. Holman and Sune Bergstrom. Lipoxidase or Unsaturated-Fat Oxidase. In
"The Enzymes," Vol. II, Chapter 60, Eds. J. B. Sumner and K.
Myrback, Academic Press, New York, pp.
559-580 (1951).
48. Pao-Tung Huang, Ralph T. Holman and
William M. Potts. Spectrophotometric and
Chromatographic Investigations of the Oil of Sapium
sebiferum. J. Am. Oil Chem. Soc. 26, 405-407 (1949).
49. Leah Cohadas Berk, Norman Kretchmer, Ralph
T. Holman and George O. Burr. Microdetermination of Unsaturated Fatty Acids by
Alkali Isomerization. Anal. Chem. 22,
718-720 (1950).
50. Herman Schlenk and Ralph T. Holman. Separation and Stabilization of Fatty Acids
by Urea Complexes. J. Am. Chem. Soc. 72, 5001-5004 (1950).
51. Hermann Schlenk and Ralph T. Holman. The Urea Complexes of Unsaturated Fatty
Acids. Science 112, 19-20 (1950).
52. Ralph T. Holman. Metabolism of Isomers of Linoleic and
Linolenic Acids (18399). Proc. Soc. Exp.
Biol. Med. 76, 100-102 (1951).
53. Ralph T. Holman. Fatty Acids in Nutrition. Proc. Third Conference on Research, Am. Meat
Inst., pp. 1-10 (1951).
54. Ralph T. Holman. Die Rolle der Fettsauren in der
Ernahrung. Fette Seifen 53, 332-336 (1951).
55. Ralph T. Holman and Nils Andreas
Sorensen. Spectral and Oxidation Studies
on Matricaria Ester (n-Decadiene-2,8-diyne-4,6-oic
Acid Methyl Ester). Acta Chem. Scand. 4,
416-421 (1950).
56. Ralph T. Holman. Chromatography of Fatty Acids and Related
Substances. Prog. Chem. Fats Other
Lipids 1, 104-126 (1952).
57. Robert S. Harris and Ralph T. Holman. Essential Fatty Acids. In "The Vitamins," Vol. II, Eds.
Sebrell and Harris, Academic Press, New York,
Chapter 7, pp. 267-319 (1954).
58. Ralph T. Holman. Autoxidation of Fats and Related
Substances. Prog. Chem. Fats Other
Lipids 2, 51-98 (1954).
59. Ralph T. Holman. Mode of Action of Lipoxidase. Trans. Am. Assoc. Cereal Chem. 11, 135-146 (1953).
60. Ralph T. Holman and Sheldon I.
Greenberg. Highly Unsaturated Fatty
Acids. I. A Survey of Possible Animal
Sources. J. Am. Oil Chem. Soc. 30, 600-601
(1953).
61. Ahmed M. Abu-Nasr, William M. Potts and
Ralph T. Holman. Highly Unsaturated
Fatty Acids. II. Fractionation by Urea Inclusion
Compounds. J. Am. Oil Chem. Soc. 31, 16-20 (1954).
62. Ahmed M. Abu-Nasr and Ralph T.
Holman. Highly Unsaturated Fatty
Acids. III. Isolation of Methyl
Eicosapentaenoate, Ethyl Docosapentaenoate, and Ethyl Docosahexaenoate from Cod
Liver Oil Esters by Chromatography. J.
Am. Oil Chem. Soc. 31, 41-45 (1954).
63. Hilda F. Wiese, Ralph T. Holman and Arild
E. Hansen. Spectrographic Evidence of
Deficiency of Unsaturated Fatty Acids in Serum and Tissues of Dogs on a Low Fat
Diet. Fed. Proc. 9, 374 (1950). (Abstract)
64. Hermann Schlenk and Ralph T. Holman. Methanolysis of Triglycerides by an Anion
Exchange Resin. J. Am. Oil Chem. Soc. 30, 103-104 (1953).
65. Ralph T. Holman. Nutritional Value of Fat. Cherry-Burrill Circle, March-April, pp.
11-13, 24 (1954).
66. Ralph T. Holman. The Nutritive Values of Fats. Milk Plant Monthly, March, pp. 33-34, 42
(1954).
66a. Annual Report of The Hormel Institute,
1951-52.
66b. Annual Report of The Hormel Institute,
1952-53.
66c. Eldon G. Hill, Ralph T. Holman and W. O.
Caster. Requirement of Swine for Dietary
Linoleate. Fed. Proc. 20, No. 1, Part I, March (1961). (Abstract)
66d. Annual Report of The Hormel Institute,
1953-54.
66e. Annual Report of The Hormel Institute,
1954-55.
66f. Annual Report of The Hormel Institute,
1955-56.
67. Ralph T. Holman and Siret Ener. Use of Urea-Inclusion Compound Containing
Essential Fatty Acid in an Experimental Diet.
J. Nutr. 53, 461-468 (1954).
68. Ralph T. Holman. Removing Charcoal from the Skin. Chemist-Analyst 43, 80 (1954).
69. Ralph T. Holman. Measurement of Lipoxidase Activity. In "Methods of Biochemical
Analysis," Ed. D. Glick,
Interscience Publ., New York, pp. 113-119 (1955).
70. Ralph T. Holman and D. P. Hanks. Isolation of 2,4-Dodecadienoic Acid from the
Seed Oil of Sebestiana lingustrina. J. Am. Oil Chem. Soc. 32, 356-357 (1955).
71. Ralph T. Holman. The Nutritional Significance of Essential
Fatty Acids. Food Nutr. News 26, 1 and 4 (1955).
72. Ahmed M. Abu-Nasr and Ralph T.
Holman. Isomerization of Polyunsaturated
Fatty Acids and Their Esters by Sodium Amide in Liquid Ammonia. J. Am. Oil Chem. Soc. 32, 414-418 (1955).
73. J. J. Peifer and Ralph T. Holman. Essential Fatty Acids, Diabetes, and
Cholesterol. Arch. Biochem. Biophys. 57, 520-521 (1955).
74. Ralph T. Holman. Function and Metabolism of Essential Fatty
Acids. In "Biochemical Problems of
Lipids." Proceedings of the Second
International Conference, University of Ghent, Eds. G. Popjak and E. Le Breton,
July 1955, Butterworths Scientific Publications, London, pp. 463-471 (1956).
75. Ralph T. Holman. The Function of Essential Fatty Acids. Sven. Kem. Tidskr. 68, 282-290 (1956).
76. Ralph T. Holman. Measurement of Polyunsaturated Fatty
Acids. In "Methods of Biochemical
Analysis," Vol. IV, Ed. D. Glick, Interscience Publ., New York, pp. 99-138
(1957).
77. Ralph T. Holman and Page R.
Edmondson. Near-Infrared Spectra of
Fatty Acids and Some Related Substances.
Anal. Chem. 28, 1533-1538 (1956).
78. Editors (Holman, Lundberg and
Malkin): Progress in the Chemistry of
Fats and Other Lipids, Pergamon Press, London, Vol. I, 186 pages, 1952.
79. Editors (Holman, Lundberg and
Malkin): Progress in the Chemistry of
Fats and Other Lipids, Pergamon Press, London, Vol. II, 347 pages, 1954.
80. Editors (Holman, Lundberg and
Malkin): Progress in the Chemistry of
Fats and Other Lipids, Pergamon Press, London, Vol. III, 475 pages, 1955.
81. Ralph T. Holman and Erik
Aaes-Jorgensen. Effects of trans Fatty Acid Isomers upon Essential Fatty
Acid Deficiency in Rats. Proc. Soc. Exp.
Biol. Med. 93, 175-179 (1956).
82. S. Kuramoto, J. J. Jezeski and R. T.
Holman. Displacement Separation of Some
of the Component Fatty Acids of Milk Fat.
J. Dairy Sci. 40, 314-322 (1957).
83. W. Montag, E. Klenk, H. Hayes and R. T.
Holman. The Eicosapolyenoic Acids
Occurring in the Glycerophosphatides of Beef Liver. J. Biol. Chem. 227,
53-60 (1957).
84. Ralph T. Holman. The Lipids in Relation to
Atherosclerosis. Am. J. Clin. Nutr. 8, 95-103 (1960).
85. Ralph T. Holman, Herbert Hayes, Haqvin
Malmros and Gerhard Wigand. Effects of
Dietary Fat upon Plasma Polyunsaturated Acids.
Proc. Soc. Exp. Biol. Med. 96, 705-709
(1957).
86. Ralph T. Holman. Essential Fatty Acids. Nutr. Rev. 16,
33-35 (1958).
87. Ralph T. Holman, Herbert Hayes and Page R.
Edmondson. Analysis of Unsaturated Fatty
Acids. In "Essential Fatty
Acids," Proc. Fourth International Conf. on Biochem. Prob. of Lipids, Oxford, July 15-18,
1957, Butterworths Scientific Publications, pp. 9-15 (1958).
88. Ralph T. Holman and Herbert Hayes. Determination of Polyunsaturated Acids in
Lipides of Plasma and Tissue. Anal.
Chem. 30, 1422-1425 (1958).
89. Eldon G. Hill, Egis L. Warmanen, Herbert
Hayes and Ralph T. Holman. Effects of
Essential Fatty Acid Deficiency in Young Swine (23192). Proc. Soc. Exp. Biol. Med. 95, 274-278 (1957).
90. Ralph T. Holman, Siret Ener and Page R.
Edmondson. Detection and Measurement of cis Unsaturation in Fatty Acids. Arch. Biochem. Biophys. 80, 72-79 (1959).
91. Erik Aaes-Jorgensen and Ralph T.
Holman. Essential Fatty Acid
Deficiency. I. Content of Polyenoic Acids in Testes and
Heart as an Indicator of EFA Status. J.
Nutr. 65, 633-641 (1958).
92. Erik Aaes-Jorgensen, E. E. Leppik, H. W.
Hayes and Ralph T. Holman. Essential
Fatty Acid Deficiency. II. In Adult Rats. J. Nutr. 66,
245-259 (1958).
93. Ralph T. Holman. The Separation of Fatty Acids. Experientia 14,
121-127 (1958).
94. Ralph T. Holman, Christense Nickell,
Orville S. Privett and Page R. Edmondson.
Detection and Measurement of Hydroperoxides by Near Infrared
Spectrophotometry. J. Am. Oil Chem. Soc.
35, 422-425 (1958).
95. Ralph T. Holman and Sheldon I.
Greenberg. A Note on the Toxicities of
Methyl Oleate Peroxide and Ethyl Linoleate Peroxide. J. Am. Oil Chem. Soc. 35, 707 (1958).
96. H. K. Mangold, H. Hayes and R. T.
Holman. Estudios sobre los eteres de
glicerilo y los aldehidos grasos. Grasas
Aceites (Seville) 10, 148-149 (1959).
97. R. T. Holman. Purity of Compounds. In "Essential Fatty Acids," Ed. H.
M. Sinclair, Academic Press, New York, and Butterworth, London, pp. 238-241
(1958).
98. R. T. Holman and E. Aaes-Jorgensen. Relationships Between Polyunsaturated Fatty
Acids and Circulating Cholesterol. In
"Essential Fatty Acids," Ed. H. M. Sinclair, Butterworths Scientific
Publications, London, pp. 156-157 (1958).
99. Erik Aaes-Jorgensen, Orville S. Privett
and Ralph T. Holman. Essential Fatty
Acid Activities of Hydrocarbons and Alcohols Analogous to Linoleate and
Linolenate. J. Nutr. 67, 413-421 (1959).
100. Orville
S. Privett, Erik Aaes-Jorgensen, Ralph T. Holman and Walter O.Lundberg. The Effect of Concentrates of Polyunsaturated
Acids from Tuna Oil upon Essential Fatty Acid Deficiency. J. Nutr. 67,
423-432 (1959).
101. James
J. Peifer and Ralph T. Holman. Effect of
Saturated Fat upon Essential Fatty Acid Metabolism of the Rat. J. Nutr. 68,
155-168 (1959).
102. Ralph
T. Holman and Carl Widmer.
Polyunsaturated Fatty Acids in Beef Heart Mitochondria and Derived Enzymically Active
Lipoprotein Fractions. J. Biol. Chem. 234, 2269-2271 (1959).
103. Ralph
T. Holman. Essential Fatty Acids in
Nutrition and Metabolism. A.M.A. Arch.
Int. Med. 105, 33-38 (1960).
104. Ralph
T. Holman. Food Composition and Method
of Preserving Same. U. S. Patent
2,875,000 (1959).
105. Warren
J. Warwick, Ralph T. Holman, Paul G. Quie and Robert A. Good. Chylous Ascites and Lymphedema. AMA Am. J. Dis. Child. 98, 317-329 (1959).
106. Ralph
T. Holman. The Ratio of
Trienoic:Tetraenoic Acids in Tissue Lipids as a Measure of Essential Fatty Acid
Requirement. J. Nutr. 70, 405-410 (1960).
107. Ralph
T. Holman and James J. Peifer.
Acceleration of Essential Fatty Acid Deficiency by Dietary
Cholesterol. J. Nutr. 70, 411-417 (1960).
108. Ralph
T. Holman. The Lipids in Relation to
Atherosclerosis. Am. J. Clin. Nutr. 8, 95-103 (1960).
109. Hermann
Schlenk, H. K. Mangold, J. L. Gellerman, W. E. Link, R. A. Morrissette, R. T.
Holman and H. Hayes. Comparative
Analytical Studies of Fatty Acids of the Alga Chlorella
pyrenoidosa. J. Am. Oil Chem. Soc. 37, 547-552 (1960).
110. O. S.
Privett, F. J. Pusch, R. T. Holman and W. O. Lundberg. Essential Fatty Acid Properties of Tuna,
Herring and Menhaden Oils. J. Nutr. 71, 66-69 (1960).
111. Ralph
T. Holman. Factors Influencing the
Requirement for Polyunsaturated Fatty Acids.
Am. J. Clin. Nutr. 8, 403-410
(1960).
112. E.
Aaes-Jorgensen, O. S. Privett and R. T. Holman.
Essential Fatty Acid Deficiency in Rats.
In "Biochemistry of Lipids," Pergamon Press, Oxford, pp.
136-142 (1960).
113. Ralph
T. Holman. Enzymes and Polyunsaturated
Fatty Acids. In "Food
Enzymes," Chapter 6, Ed. H. W. Schultz, AVI Publishing Co., Westport, CT,
pp. 75-83 (1960).
114. Ralph
T. Holman. Behovet av essentiella
fettsyror. (Requirement of Essential
Fatty Acids), in Swedish.
Naringsforshning, pp. 56-58 (1960).
115. Lindsay
J. Morris, Ralph T. Holman and Krister Fontell. Alteration of Some Long-Chain Esters During
Gas-Liquid Chromatography. J. Lipid Res.
1, 412-420 (1960).
116. Krister
Fontell, Ralph T. Holman and Georg Lambertsen.
Some New Methods for Separation and Analysis of Fatty Acids and Other
Lipids. J. Lipid Res. 1, 391-404 (1960).
117. John
A. Williams, Akhila Sharma, Lindsay J. Morris and Ralph T. Holman. Fatty Acid Composition of Feces and Fecaliths
(26052). Proc. Soc. Exp. Biol. Med. 105, 192-195 (1960).
118. L. J.
Morris, R. T. Holman and K. Fontell. Vicinally Unsaturated Hydroxy Acids in Seed
Oils. J. Am. Oil Chem. Soc. 37, 323-327 (1960).
119. W. O.
Caster and Ralph T. Holman. Statistical
Study of the Relationship Between Dietary Linoleate and the Fatty Acids of
Heart and Blood Lipids. J. Nutr. 73,
337-346 (1961).
120. Eldon
G. Hill, E. L. Warmanen, C. L. Silbernick and Ralph T. Holman. Essential Fatty Acid Nutrition in Swine. I.
Linoleate Requirement Estimated from Triene:Tetraene Ratio of Tissue
Lipids. J. Nutr. 74, 335-341 (1961).
121. Lindsay
J. Morris, Ralph T. Holman and Krister Fontell.
Naturally Occurring Epoxy Acids:
I. Detection and Evaluation of
Epoxy Fatty Acids by Paper, Thin-Layer, and Gas-Liquid Chromatography. J. Lipid Res. 2,
68-76 (1961).
122. Lindsay
J. Morris and Ralph T. Holman. Naturally
Occurring Epoxy Acids: II. Detection and
Measurement of Long-Chain Epoxy Acids by Near Infrared Spectrophotometry. J. Lipid Res. 2,
77-82 (1961).
123. L. J.
Morris, H. Hayes and R. T. Holman.
Naturally-Occurring Epoxy Acids.
III. Methods for Their
Isolation. J. Am. Oil Chem. Soc. 38, 316-321 (1961).
124. Eduardo
Vioque and Ralph T. Holman. p-Phenylazophenacyl Esters of Some Acids
Derived from or Related to Lipides.
Anal. Chem. 33, 1444 (1961).
125. E.
Vioque, L. J. Morris and R. T. Holman.
Minor Components of Olive Oils.
II. trans-9,10-Epoxystearic Acid in Orujo Oil. J. Am. Oil Chem. Soc. 38, 489-492 (1961).
126. Ralph
T. Holman. How Essential Are Fatty
Acids? J. Am. Med. Assoc. 178, 930-933 (1961).
127. Leland
K. Dahle and Ralph T. Holman. Modified
Iodometric Method for Semi-microdetermination of Lipide Peroxides. Anal. Chem. 33,
1960-1961 (1961).
128. E.
Vioque and R. T. Holman. Quantitative
Estimation of Esters by Thin-Layer Chromatography. J. Am. Oil Chem. Soc. 39, 63-66 (1962).
129. R. T.
Holman. Essential Fatty Acid
Requirement. Int. Dairy Fed. 1962 Bull.,
Part II, pp. 1-6 (1962).
130. Ralph
T. Holman. Some Modern Methods of
Separation and Analysis Applicable to Fish Oils. In "Fish in Nutrition," Eds. Eirik
Heen and Rudolf Kreuzer, Fishing News (Books) Ltd., Ludgate House, London, pp.
117-124 (1962).
131. Ara
Chalvardjian, Lindsay J. Morris and Ralph T. Holman. Effect of Dietary Epoxyoleic Acid Upon
Rats. J. Nutr. 76, 52-58 (1962).
132. W. O.
Caster, Philip Ahn, Eldon G. Hill, H. Mohrhauer and Ralph T. Holman. Determination of Linoleate Requirement of
Swine by a New Method of Estimating Nutritional Requirement. J. Nutr. 78,
147-154 (1962).
133. Ralph
T. Holman. Polyunsaturated Fats in
Nutrition. Proc. Fourteenth Res. Conf.
Am. Meat Inst. Fdn., pp. 85-87 (1962).
134. Leland
K. Dahle, Eldon G. Hill and Ralph T. Holman.
The Thiobarbituric Acid Reaction and the Autoxidations of
Polyunsaturated Fatty Acid Methyl Esters.
Arch. Biochem. Biophys. 98, 253-261
(1962).
134a. Ralph
T. Holman. Djurorganismens behov av
essentiella fettsyror. Abstract #11 in
Nordiska kemistmotet, Abo, Finland, 1962.
135. E.
Vioque and R. T. Holman.
Characterization of the Ketodienes Formed in the Oxidation of Linoleate by
Lipoxidase. Arch. Biochem. Biophys. 99, 522-528 (1962).
136. Hans
Mohrhauer and Ralph T. Holman. The
Effect of Dose Level of Essential Fatty Acids upon Fatty Acid Composition of
the Rat Liver. J. Lipid Res. 4, 151-159 (1963).
137. Georg
Lambertsen and Ralph T. Holman. Partial
Characterization of the Hydrocarbons of Herring Oil. Acta Chem. Scand. 17, 281-282 (1963).
138. W. O.
Caster, Eldon G. Hill and Ralph T. Holman.
Estimation of Essential Fatty Acid Intake in Swine. J. Anim. Sci. 22,
389-392 (1963).
139. Hans
Mohrhauer and Ralph T. Holman. The
Effect of Dietary Essential Fatty Acids upon Composition of Polyunsaturated
Fatty Acids in Depot Fat and Erythrocytes of the Rat. J. Lipid Res. 4,
346-350 (1963).
140. Hans
Mohrhauer and Ralph T. Holman.
Alteration of the Fatty Acid Composition of Brain Lipids by Varying
Levels of Dietary Essential Fatty Acids. J. Neurochem. 10, 523-530 (1963).
141. Ralph
T. Holman and Hans Mohrhauer. A
Hypothesis Involving Competitive Inhibitions in the Metabolism of
Polyunsaturated Fatty Acids. Acta Chem.
Scand. 17, S84-S90 (1963).
142. Rene
Maier and Ralph T. Holman. Naturally
Occurring Triglycerides Possessing Optical Activity in the Glycerol
Moiety. Biochemistry 3, 270-274 (1964).
143. Editors
(Holman, Lundberg and Malkin): Progress
in the Chemistry of Fats and Other Lipids.
Pergamon Press, London, Vol. IV, 289 pages, 1957.
144. Editors
(Holman, Lundberg and Malkin): Progress
in the Chemistry of Fats and Other Lipids.
Pergamon Press, London, Vol. V, 311 pages, 1958.
145. Editors
(Holman, Lundberg and Malkin): Progress
in the Chemistry of Fats and Other Lipids.
Pergamon Press, London, Vol. VI, 364 pages, 1963.
146. Hans
Mohrhauer and Ralph T. Holman. Effects
of Dietary Essential Fatty Acids upon Polyunsaturated Fatty Acids in Rat Heart
Tissue. Biochem. Probl. Lipids, B.B.A.
Library 1, 446-452 (1963).
147. Hans
Mohrhauer and Ralph T. Holman. Effect of
Linolenic Acid Upon the Metabolism of Linoleic Acid. J. Nutr. 81,
67-74 (1963).
148. Ralph
T. Holman. Hiawatha's Meeting. J. Am. Oil Chem. Soc. 40, 16, 46-47, 54 (1963).
149. Joseph
J. Rahm and Ralph T. Holman. The
Relationship of Single Dietary Polyunsaturated Fatty Acids to Fatty Acid
Composition of Lipids from Subcellular Particles of Liver. J. Lipid Res. 5,
169-176 (1964).
150. Ralph
T. Holman, W. O. Caster and Hilda F. Wiese.
The Essential Fatty Acid Requirement of Infants and the Assessment of Their Dietary Intake of Linoleate by Serum
Fatty Acid Analysis. Am. J. Clin. Nutr. 14, 70-75 (1964).
151. Ralph
T. Holman, W. O. Caster and Hilda F. Wiese.
Estimation of Linoleate Intake of Men from Serum Lipid Analysis. Am. J. Clin. Nutr. 14, 193-196 (1964).
152. Joseph
J. Rahm and Ralph T. Holman. Effect of
Linoleic Acid upon the Metabolism of Linolenic Acid. J. Nutr. 84,
15-19 (1964).
153. Joseph
J. Rahm and Ralph T. Holman. Studies of
the Metabolism of Polyunsaturated Acids by Short-term Experiments. J. Nutr. 84,
149-154 (1964).
154. Ralph
T. Holman. Nutritional and Metabolic
Interrelationships Between Fatty Acids.
Fed. Proc. 23, 1062-1067 (1964).
155. Ralph
T. Holman. Some Studies in Essential
Fatty Acid Metabolism and Nutrition. In
"Metabolism of Lipids as Related to Atherosclerosis," Ed. F. A. Kummerow, Thomas Publ., Springfield,
IL, pp. 186-197 (1965).
156. Ralph
T. Holman and H. H. Hofstetter. The
Fatty Acid Composition of the Lipids from Bovine and Porcine Reproductive
Tissues. J. Am. Oil Chem. Soc. 42, 540-544 (1965).
157. H. H.
Hofstetter, N. Sen and R. T. Holman. Characterization
of Unsaturated Fatty Acids by Gas-Liquid Chromatography. J. Am. Oil Chem. Soc. 42, 537-540 (1965).
158. Zvi
Selinger and Ralph T. Holman. The
Effects of trans,trans-Linoleate upon the
Metabolism of Linoleate and Linolenate and the Positional Distribution of
Linoleate Isomers in Liver Lecithin.
Biochim. Biophys. Acta 106, 56-62
(1965).
159. Ralph
T. Holman, H. W. Hayes, Aime Rinne and Lars Soderhjelm. Polyunsaturated Fatty Acids in Serum of
Infants Fed Breast Milk or Cow's Milk.
Acta Paediatr. Scand. 54, 573-577
(1965).
160. Berndt
E. Hagstrom and Ralph T. Holman. The
Effect of Free Fatty Acids upon the Fertilization of the Eggs of the Sea
Urchin. Protoplasma 60, 211-217 (1965).
161. Hans
Mohrhauer and Ralph T. Holman. Tracer
Experiments to Assess Metabolic Conversions of Polyunsaturated Fatty
Acids. J. Am. Oil Chem. Soc. 42, 639-643 (1965).
162. Ralph
T. Holman, Hans Mohrhauer, Eldon G. Hill and W. O. Caster. Muscular Dystrophy: A Problem in Polyunsaturated Fatty Acid
Metabolism? Am. J. Clin. Nutr. 16, 453 (1965).
163. Jorge
J. Casal and Ralph T. Holman. The Effect
of Kind of Dietary Carbohydrate upon the Composition of Liver Fatty Acids of
the Rat. J. Am. Oil Chem. Soc. 42, 1134-1137 (1965).
164. Pilar
Teresa Garcia and Ralph T. Holman.
Competitive Inhibitions in the Metabolism of Polyunsaturated Fatty Acids
Studied via the Composition of Phospholipids, Triglycerides and Cholesteryl
Esters of Rat Tissues. J. Am. Oil Chem.
Soc. 42, 1137-1141 (1965).
165. W. O.
Caster, Hans Mohrhauer and Ralph T. Holman.
Effects of Twelve Common Fatty Acids in the Diet upon the Composition of
Liver Lipid in the Rat. J. Nutr. 89, 217-225 (1966).
166. Howard
W. Sprecher, Rene Maier, M. Barber and Ralph T. Holman. Structure of an Optically Active
Allene-containing Tetraester Triglyceride Isolated from the Seed Oil of Sapium sebiferum. Biochemistry 4,
1856-1863 (1965).
167. Ralph
T. Holman. Metabolism of Polyunsaturated
Acids. In "Symposia of the Swedish
Nutrition Foundation. IV. Polyunsaturated Fatty Acids as
Nutrients," Eds. G. Blix, Almqvist and Wiksell, Stockholm, pp. 31-42
(1966).
168. Ralph
T. Holman. General Introduction to
Polyunsaturated Acids. Prog. Chem. Fats
Other Lipids 9, 3-12 (1966).
169. Ralph
T. Holman and Joseph J. Rahm. Analysis
and Characterization of Polyunsaturated Fatty Acids. Prog. Chem. Fats Other Lipids 9, 13-90 (1966).
170. W. W.
Christie and R. T. Holman. Mass
Spectrometry of Lipids. I. Cyclopropane Fatty Acid Esters. Lipids 1,
176-182 (1966).
171. Ralph
T. Holman, Manfred Deubig and Herbert Hayes.
Pyrolysis Chromatography of Lipids.
I. Mass Spectrometric
Identification of Pyrolysis Products of Hydrocarbons. Lipids 1,
247-253 (1966).
172. Balwant
Ahluwalia and Ralph T. Holman. Fatty
Acid Distribution in the Bovine Pre- and Postpartum Testis. Lipids 1,
197-201 (1966).
173. R. T.
Holman. Special AOCS Award Highlights
Symposium Honoring George Burr. J. Am.
Oil Chem. Soc. 43, 152A-154A (1966).
173a. Annual
Report of The Hormel Institute, 1956-57.
173b. Annual
Report of The Hormel Institute, 1957-58.
173c. Annual
Report of The Hormel Institute, 1958-59.
173d. Annual
Report of The Hormel Institute, 1959-60.
173e. Annual
Report of The Hormel Institute, 1960-61.
173f. Annual
Report of The Hormel Institute, 1961-62.
173g. Annual
Report of The Hormel Institute, 1962-63.
173h. Annual
Report of The Hormel Institute, 1963-64.
173i. Annual
Report of The Hormel Institute, 1964-65.
173j. Annual
Report of The Hormel Institute, 1965-66.
173k. Ralph T.
Holman. Techniques of Biological
Chemistry. Review of book by R. T.
Holman, Science 151, 678 (1965).
173l. Ralph
T. Holman. Review of book "Analysis
of Fats and Oils," Anal. Chem. 32
(11), 68A and 72A (1960).
173m. B.
Ahluwalia, J. J. Rahm, H. Mohrhauer and R. T. Holman. Influence of Dietary Polyunsaturated Fatty
Acids upon Fatty Acid Composition of Rat Testes. J. Dairy Sci. 48,
819 (1965).
174. Cecil
B. Johnson and Ralph T. Holman. Mass
Spectrometry of Lipids. II.
Monoglycerides, Their Diacetyl Derivatives and Their Trimethylsilyl
Ethers. Lipids 1, 371-380 (1966).
175. Terry
M. Groff, Henry Rakoff and Ralph T. Holman.
Mass Spectrometry of Lipids.
Isomeric Methyl Nonynoates and the Corresponding Nonenoates and
Dideutero-nonenoates. Ark. Kemi 29, 179-190 (1968).
176. Joseph
J. Rahm and Ralph T. Holman. Essential
Fatty Acids. In "The Vitamins," Vol. III, Second Edition, Eds. W. H.
Sebrell, Jr. and Robert S. Harris, Academic Press, New York, pp. 303-339
(1971).
177. Howard
W. Sprecher, H. J. Dutton, F. D. Gunstone, P. T. Sykes and Ralph T.
Holman. Metabolic Conversions and the
Positional Distributions in Liver Lecithin of Some Unnatural Dienoic Acids in
the Rat. Lipids 2, 122-126 (1967).
178. Hans
Mohrhauer, Joseph J. Rahm, Joseph Seufert and Ralph T. Holman. Metabolism of Linoleic Acid in Relation to
Dietary Monoenoic Fatty Acids in the Rat.
J. Nutr. 91, 521-527 (1967).
179. Hans
Mohrhauer and Ralph T. Holman.
Metabolism of Linoleic Acid in Relation to Dietary Saturated Fatty Acids
in the Rat. J. Nutr. 91, 528-534 (1967).
180. B.
Ahluwalia, G. Pincus and R. T. Holman.
Essential Fatty Acid Deficiency and Its Effects upon Reproductive Organs
of Male Rabbits. J. Nutr. 92, 205-214 (1967).
181. Ralph
T. Holman. The Role of Dietary Fat in
Human Health. A Report of the Food and
Nutrition Board, National Academy of Sciences--National Research Council,
Publication 575, written by the Committee on Fats in Human Nutrition, pp. 1-32 (1958).
182. Ralph
T. Holman. Dietary Fat and Human Health. A Report of the Food and Nutrition Board,
National Academy of Sciences--National Research Council, written by the
Committee on Fats in Human Nutrition, Publication 1157, pp. 1-51 (1966).
183. R. T.
Holman. Fat Metabolism. Taped television lecture in Minnesota
Feasibility Study, Austin Junior College - Rochester Junior College, August
(1966).
184. Kwok
K. Sun and Ralph T. Holman. Mass
Spectrometry of Lipid Molecules. J. Am.
Oil Chem. Soc. 45, 810-817 (1968).
185. Hans
Mohrhauer, Kirsten Christiansen, Minerva V. Gan, Manfred Deubig and Ralph T.
Holman. Chain Elongation of Linoleic
Acid and Its Inhibition by Other Fatty Acids in
Vitro. J. Biol. Chem. 242, 4507-4514 (1967).
186. William
W. Christie and Ralph T. Holman.
Synthesis and Characterization of the Complete Series of
Methylene-Interrupted cis,cis-Octadecadienoic
Acids. Chem. Phys. Lipids 1, 407-423 (1967).
187. Cecilia
Pudelkewicz, Joseph Seufert and Ralph T. Holman. Requirement of the Female Rat for Linoleic
and Linolenic Acids. J. Nutr. 94, 138-146 (1968).
188. Cecelia
Pudelkewicz and Ralph T. Holman.
Positional Distribution of Fatty Acids in Liver Lecithin of Rats as a
Function of Dietary Linoleate or Linolenate.
Biochim. Biophys. Acta 152, 340-345
(1968).
189. Yves
L. Marcel and Ralph T. Holman. Synthesis
of 14C-Labelled
Polyunsaturated Fatty Acids. Chem. Phys.
Lipids 2, 173-182 (1968).
190. Ronald
C. Reitz, William E. M. Lands, William W. Christie and Ralph T. Holman. Effects of Ethylenic Bond Position upon
Acyltransferase Activity with Isomeric cis,cis-Octadecadienoyl
Coenzyme A Thiol Esters. J. Biol. Chem. 243, 2241-2246 (1968).
191. Hans
Mohrhauer, Kirsten Christiansen, Minerva Gan, Manfred Deubig and Ralph T.
Holman. Improved Method for the
Preparation of Malonyl Coenzyme A. J.
Lipid Res. 9, 398 (1968).
192. Kirsten
Christiansen, Yves Marcel, Minerva V. Gan, Hans Mohrhauer and Ralph T.
Holman. Chain Elongation of - and
-Linolenic Acids and the Effect of Other Fatty Acids on Their Conversion in vitro.
J. Biol. Chem. 243, 2969-2974 (1968).
193. Y. L.
Marcel, K. Christiansen and R. T. Holman.
The Preferred Metabolic Pathway from Linoleic Acid to Arachidonic Acid in vitro.
Biochim. Biophys. Acta 164, 25-34 (1968).
194. B.
Ahluwalia and R. T. Holman. Fatty Acid
Composition of Lipids of Bull, Boar, Rabbit and Human Semen. J. Reprod. Fert. 18, 431-437 (1969).
195. Ralph
T. Holman, Peter O. Egwim and William W. Christie. Substrate Specificity of Soybean
Lipoxidase. J. Biol. Chem. 244, 1149-1151 (1969).
196. Ralph T.
Holman. Essential Fatty Acid
Deficiency. Prog. Chem. Fats Other
Lipids 9, 275-348 (1971).
197. Editor: Progress in the Chemistry of Fats and Other
Lipids, Pergamon Press, Oxford, Vol. 7, 308 pages (1964).
198. Editor: Progress in the Chemistry of Fats and Other
Lipids, Pergamon Press, Oxford, Vol. 8, 436 pages (1966).
199. Editor: Progress in the Chemistry of Fats and Other
Lipids, Pergamon Press, Oxford, Vol. 9, 718 pages (1971).
200. Editor: Progress in the Chemistry of Fats and Other
Lipids, Pergamon Press, Oxford, Vol. 10,
466 pages (1970).
201. W. W.
Christie, D. Rebello and Ralph T. Holman.
Mass Spectrometry of Derivatives of Cyclopentenyl Fatty Acids. Lipids 4,
229-231 (1969).
202. Kirsten
Christiansen, V. Mahadevan, C. V. Viswanathan and R. T. Holman. Mass Spectrometry of Long-Chain Aliphatic
Aldehydes, Dimethyl Acetals and
Alk-1-enyl Ethers. Lipids 4, 421-427 (1969).
203. Gustav
Graff, Yves L. Marcel and Ralph T. Holman.
Analysis of Labeled Fatty Acids by Argentation Chromatography of Their
Methyl Esters on Glass Fiber Sheets. J.
Chromatogr. Sci. 7, 298-299 (1969).
204. Kirsten
Christiansen, Minerva V. Gan and Ralph T. Holman. Sex Differences in the Metabolism of Fatty
Acids in vitro. Biochim. Biophys. Acta 187, 19-25 (1969).
205. Kwok
K. Sun, Herbert W. Hayes and Ralph T. Holman.
Thermal and Mass Spectrometric Fragmentation of Esters of Deuterated
Long Chain Carboxylic Acids. Org. Mass Spectrom. 3,
1035-1042 (1970).
206. H. M.
Jenkin, L. E. Anderson, R. T. Holman, I. A. Ismail and F. D. Gunstone. Effect
of Isomeric cis-Octadecenoic Acids on the
Growth of Leptospira interrogans Serotype patoc.
J. Bacteriol. 98, 1026-1029 (1969).
207. W. J.
Baumann, J. Seufert, H. W. Hayes and R. T. Holman. Mass Spectrometric Analysis of Long-Chain
Esters of Diols. J. Lipid Res. 10, 703-709 (1969).
208. H. M.
Jenkin, L. E. Anderson, R. T. Holman, I. A. Ismail and F. D. Gunstone. The Effect of Isomeric cis-Octadecenoic Acids on the Growth of Monkey Kidney Cells (LLC-MK2). Exp. Cell Res. 59,
1-5 (1970).
209. Lars
Soderhjelm, Hilda F. Wiese and Ralph T. Holman.
The Role of Polyunsaturated Acids in Human Nutrition and
Metabolism. Prog. Chem. Fats Other
Lipids 9, 555-585 (1971).
210. Ralph
T. Holman. Biological Activities of and
Requirements for Polyunsaturated Acids.
Prog. Chem. Fats Other Lipids 9,
607-682 (1971).
211. Ralph
T. Holman. Metabolic Conversions of
Polyunsaturated Fatty Acids. In
"Proceedings of the 1968 Deuel Conference on Lipids: The Turnover of Lipids and Lipoproteins,"
Chapter 8, Eds. G. Cowgill, D. L. Estrich and P. D. Wood, U. S. Government
Printing Office, pp. 75-77 (1969).
212. John
R. Paulsrud, Sheila E. Stewart, Gustav Graff and Ralph T. Holman. Desaturation of Saturated Fatty Acids by Rat
Liver Microsomes. Lipids 5, 611-616 (1970).
213. Gustav
Graff, Patricia Szczepanik, Peter D. Klein, J. R. Chipault and Ralph T.
Holman. Identification and
Characterization of Fully Deuterated Fatty Acids Isolated from Scenedesmus obliquus Cultured in Deuterium
Oxide. Lipids 5, 786-792 (1970).
214. W. M.
Lauer, A. J. Aasen, G. Graff and R. T. Holman.
Mass Spectrometry of Triglycerides:
I. Structural Effects. Lipids 5,
861-868 (1970).
215. A. J.
Aasen, W. M. Lauer and R. T. Holman.
Mass Spectrometry of Triglycerides:
II. Specifically Deuterated
Triglycerides and Elucidation of Fragmentation Mechanisms. Lipids 5,
869-877 (1970).
216. A. J.
Aasen, H. H. Hofstetter, B. T. R. Iyengar and R. T. Holman. Identification and Analysis of Wax Esters by
Mass Spectrometry. Lipids 6, 502-507 (1971).
217. John
K. G. Kramer, Wolfgang J. Baumann and Ralph T. Holman. Mass Spectrometric Analysis of Long Chain
Alk-1-enyl Ether Esters and Alkyl Ether Esters of Diols. Lipids 6,
492-501 (1971).
218. Ralph
T. Holman, Herbert W. Hayes, and W. W. Christie. Mass Spectra of Cyclopentenylic Acids and
Their Derivatives. Arch. Mass Spectral
Data 2, 4-27 (1971).
219. Editor: Progress in the Chemistry of Fats and Other
Lipids, Pergamon Press, Oxford, Vol. 11, 424 pages (1971).
220. Wayne
H. Heimermann and Ralph T. Holman.
Highly Optically Active Triglycerides of Sebastiana
ligustrina and Related Species.
Phytochemistry 11, 799-802 (1972).
221. Ralph
T. Holman and Patrick C. Nichols.
Characterization of the Lipids of Some Orchids. Phytochemistry 11,
333-337 (1972).
222. Gustav
Graff, Herbert W. Hayes and Ralph T. Holman.
Mass Spectra of Methyl Esters of Perdeuterio Fatty Acids. Arch. Mass Spectral Data 3, 160-165 (1972).
223. A. J.
Aasen, H. W. Hayes and R. T. Holman.
Mass Spectra of Deuterium Labeled Triglycerides. Arch. Mass Spectral Data 3, 166-191 (1972).
224. A.
Strocchi and R. T. Holman. Analysis of
Fatty Acids of Butterfat. Riv. Ital. Sostanze Grasse 48, 617-622 (1971).
225. John
R. Paulsrud, Leslie Pensler, Charles F. Whitten, Sheila Stewart and Ralph T.
Holman. Essential Fatty Acid Deficiency
in Infants Induced by Fat-Free Intravenous Feeding. Am. J. Clin. Nutr. 25, 897-904 (1972).
226. Huei-che
Chang and Ralph T. Holman. Chain
Shortening of Acyl-Coenzyme A by Rat Liver Microsomes. Biochim. Biophys. Acta 280, 17-21 (1972).
227. Robert
G. Jensen, Dennis T. Gordon, Wayne H. Heimermann and Ralph T. Holman. Specificity of Geotrichum
candidum Lipase with Respect to Double Bond Position in Triglycerides
Containing cis-Octadecenoic Acids. Lipids 7,
738-741 (1972).
228. Huei-che
Chang, James Janke, Fred Pusch and Ralph T. Holman. Effect of Double and Triple Bonds in Fatty
Acid Inhibitors upon Desaturation of Stearic Acid by Rat Liver Microsomes. Biochim. Biophys. Acta 306, 21-25 (1973).
229. Wayne
H. Heimermann, Ralph T. Holman, Dennis T. Gordon, Doris E. Kowalyshyn and
Robert G. Jensen. Effect of Double Bond
Position in Octadecenoates upon Hydrolysis of Pancreatic Lipase. Lipids 8,
45-47 (1973).
230. Patrick
C. Nichols and Ralph T. Holman.
Pyrolysis of Saturated Triglycerides.
Lipids 7, 773-779 (1972).
231. Ralph
T. Holman. Essential Fatty Acid
Deficiency in Humans. In "Dietary
Lipids and Postnatal Development,"
Raven Press, New York, pp. 127-143 (1973).
232. Ralph
T. Holman and Wayne H. Heimermann.
Identification of Components of Orchid Fragrances by Gas
Chromatography-Mass Spectrometry. Am.
Orchid Soc. Bull. 42, 678-682 (1973).
233. Bengt
A. Andersson and Ralph T. Holman.
Pyrrolidides for Mass Spectrometric Determination of the Position of the
Double Bond in Monounsaturated Fatty Acids.
Lipids 9, 185-190 (1974).
234. B. A.
Andersson, W. H. Heimermann and R. T. Holman.
Comparison of Pyrrolidides with Other Amides for Mass Spectral Determination
of Structure of Unsaturated Fatty Acids.
Lipids 9, 443-449 (1974).
235. Wolfgang
J. Baumann, Arne J. Aasen, John K. G. Kramer and Ralph T. Holman. Evidence for the Electron Impact Induced
Formation of Prominent Cyclic Acetal Ions from Aliphatic Ester Lipids. J. Org. Chem. 38,
3767-3771 (1973).
236. Ralph
T. Holman. Significance of Essential
Fatty Acids in Human Nutrition In
"Lipids," Vol. 1, Eds. R. Paoletti, G. Porcellati and G. Jacini,
Raven Press, New York, pp. 215-226 (1976).
237. Bengt
A. Andersson and Ralph T. Holman. Mass
Spectrometric Localization of Methyl Branching in Fatty Acids Using
Acylpyrrolidines. Lipids 10, 716-718 (1975).
238. Bengt
A. Andersson, William W. Christie and Ralph T. Holman. Mass Spectrometric Determination of Positions
of Double Bonds in Polyunsaturated Fatty Acid Pyrrolidides. Lipids 10,
215-219 (1975).
239. Ralph
T. Holman. Role of Essential Fatty Acids
in Human Nutrition. Yukagaku (J. Jpn.
Oil Chem. Soc.) 24, 139-144 (1975).
240. Ralph
T. Holman and Wayne H. Heimermann. The
Chemical Composition of Fragrances of Some Orchids. In "First Symposium on the Scientific
Aspects of Orchids," Eds. H. Harry Szmant and James Wemple, University of
Detroit Publ., pp. 75-89 (1976).
241. L. B.
Thien, W. H. Heimermann and R. T. Holman.
Floral Odors and Quantitative Taxonomy of Magnolia and
Liriodendron. Taxon 24, 557-568 (1975).
242. Ralph
T. Holman. Deficiency of Essential Fatty
Acids in Humans. In "Essential
Fatty Acids," Proc. of the Miles Symposium '75, Ed. W. W. Hawkins, The
Nutrition Society of Canada, pp. 45-58 (1976).
243. Pilar
Teresa Garcia, W. W. Christie, Howard M. Jenkin, Lloyd Anderson and Ralph T.
Holman. The Isomerization of 2,5- and
9,12-Octadecadienoic Acids by an Extract of Butyrivibrio
fibrisolvens. Biochim. Biophys. Acta
424, 296-302 (1976).
244. Ralph
T. Holman. Function and Biologic
Activities of Essential Fatty Acids in Man.
In "Fat Emulsions in Parenteral Nutrition," AMA Symposium on
Fat Emulsion in Parenteral Nutrition, June 5-6, 1975, Eds. H. C. Meng and
Douglas W. Wilmore, American Medical Assoc., Chicago, IL, pp. 5-14 (1976).
245. Editor: Progress in the Chemistry of Fats and Other
Lipids, Pergamon Press, Oxford, Vol. 12, 307 pages (1972).
246. Editor: Progress in the Chemistry of Fats and Other
Lipids, Pergamon Press, Oxford, Vol. 13, 283 pages (1973).
247. Editor: Progress in the Chemistry of Fats and Other
Lipids, Pergamon Press, Oxford, Vol. 14, 299 pages (1975).
248. A. J.
Valicenti and R. T. Holman. Oxidation of
Long-Chain Alcohols to Aldehydes by the Dipyridine Chromic Anhydride
Complex. Chem. Phys. Lipids 17, 389-392 (1976).
249. Jerry
Darsie, Susan K. Gosha and Ralph T. Holman.
Induction of Abnormal Fatty Acid Metabolism and Essential Fatty Acid
Deficiency in Rats by Dietary DDT. Arch.
Biochem. Biophys. 175, 262-269 (1976).
250. R. T.
Holman. Biological Significance of the
Position of the Double Bonds in Fatty Acids and
Isomerism: Effect on Metabolism and
Function of Unsaturated Fatty Acids. In
"Encyclopedia of Food Science," Vol. 3, Eds. Martin S. Peterson and Arnold H. Johnson, AVI Publ.
Co., Westport, CT, pp. 84-87 and 423-426,
respectively (1978).
251. Ralph
T. Holman. Cultivation of Cypripedium calceolus and Cypripedium reginae. Am.
Orchid Soc. Bull. 45, 415-422 (1976).
252. Ralph
T. Holman. The Deficiency of Essential
Fatty Acids. In "Polyunsaturated
Fatty Acids," Eds. Wolf-H. Kunau and Ralph T. Holman, AOCS Monograph No.
4, American Oil Chemists' Society Publishers, Champaign, IL, pp. 163-182
(1977).
253. Carl
E. Hunt, Rolf R. Engel, Siv Modler, Wade Hamilton, Susan Bissen and Ralph T.
Holman. Essential Fatty Acid Deficiency
in Neonates: Inability to Reverse
Deficiency by Topical Applications of EFA-Rich Oil. J. Pediatr. 92,
603-607 (1978).
254. W. O.
Caster, James W. Andrews, Jr., Hans Mohrhauer and Ralph T. Holman. Effect of
Essential and Nonessential Fatty Acids in Complex Mixture on Fatty
Acid
Composition of Liver Lipids. J. Nutr. 106, 1809-1816 (1976).
255. John
K. G. Kramer, Ralph T. Holman and Wolfgang J. Baumann. Mass Spectrometric Analysis of Mono- and
Dialkyl Ethers of Diols. Lipids 6,
727-733
(1971).
256. R. T.
Holman. The Effect of Structure of
Unsaturated Fatty Acids upon Chemical and Biochemical Reactions. Transactions in the symposium on
"Lipoperoxidation in Disease," August 26, 1976, published by Tokyo
Tanabe Company Limited, Tokyo, Japan (1978).
257. R. T.
Holman. Essential Fatty Acid Deficiency
in Animals. In "CRC Handbook Series
in Nutrition and Food, Section E:
Nutritional Disorders," Vol. 2,
Ed. M. Rechcigl, Jr., CRC Press, Cleveland, OH, pp. 491-515 (1978).
258. R. T.
Holman. Essential Fatty Acids in Human
Nutrition. In "Advances in
Experimental Medicine" (Function and Biosynthesis of Lipids), Ed. Nicolas
G. Bazan, Rodolfo R. Brenner and Norman M. Giusto, Plenum Publ. Corp., New
York, pp. 515-534 (1977).
259. Ralph
T. Holman. Grow the State Flower in Your
Backyard. Minn. Heritage Series, No. 2,
Minn. Dept. of Natural Resources, pp. 6-7 (1976).
260. Ralph
T. Holman. Grow Minnesota's Regal
Flower. In "The Minnesota
Volunteer," Ed. John G. McKane, Official Publ. Minn. Dept. of Natural
Resources, St. Paul, MN, Vol. 39, #227, pp. 52-57 (1976).
261. R. T.
Holman. Quantitative Chemical Taxonomy
Based upon Composition of Lipids. Prog. Chem. Fats Other Lipids 16, 9-29 (1978).
262. R. T.
Holman. Essential Fatty Acid Deficiency
in Humans. In "CRC Handbook Series
in Nutrition and Food, Section E:
Nutritional Disorders," Vol. 3, Ed. M. Rechcigl, Jr., CRC Press,
Cleveland, OH, pp. 335-368 (1978).
263. Ralph
T. Holman. Function and Metabolism of
Essential Fatty Acids. In
"Nutrition in Transition:
Proceedings, Western Hemisphere Nutrition Congress V," Eds. Philip
L. White and Nancy Selvey, American Medical Assoc. Publ., Monroe, WI, pp. 77-87
(1978).
264. Anthony
J. Valicenti, Clifford J. Chapman, Ralph T. Holman and Jacques R.
Chipault. Mass Spectrometric
Identification of C20 Fatty Acids in Bovine
Lens Using the Pyrrolidide Derivative.
Lipids 13, 190-194 (1978).
265. Ralph
T. Holman. How Essential Are Essential
Fatty Acids? J. Am. Oil Chem. Soc. 55, 774A-782A (1978); translated into Dutch
and French 1984.
265a. Ralph
T. Holman. Que Tan Esenciales Son Los
Acidos Grasos Esenciales? Arch. Latinam.
Nutr. (In Spanish) 29, 11-38 (1979).
266. Anthony
J. Valicenti, Wayne H. Heimermann and Ralph T. Holman. Mass Spectrometric Location of Triple Bonds
in Fatty Acids and Fragmentation Mechanisms of N-Acylpyrrolidines. J. Org. Chem. 44,
1068-1073 (1979).
267. Carl
E. Hunt, Rolf R. Engel and Ralph T. Holman.
Letter to the Editor. J. Pediatr.
93, 1069 (1978).
268. Eldon
G. Hill, Susan B. Johnson and Ralph T. Holman.
Intensification of Essential Fatty Acid Deficiency in the Rat by Dietary
trans Fatty Acids. J. Nutr. 109,
1759-1765 (1979).
269. Ralph
T. Holman, Lowell Smythe and Susan Johnson.
Effect of Sex and Age on Fatty Acid Composition of Human Serum
Lipids. Am. J. Clin. Nutr. 32, 2390-2399 (1979).
270. Ralph
T. Holman. The Importance of Double Bond
Position in the Metabolism of Unsaturated Fatty Acids. In "Geometrical and Positional Fatty
Acid Isomers," Chapter 10, AOCS Monograph, Eds. E. A. Emken and H. J.
Dutton, American Oil Chemists' Society, Champaign, IL, pp. 283-301 (1979).
271. Bruce
A. Evans, Jeffrey K. Yao, Ralph T. Holman, W. Stephen Brimijoin, Edward H.
Lambert and Peter James Dyck. Structural
and Biochemical Effects of Essential Fatty Acid Deficiency on Peripheral Nerve. J. Neuropathol. Exp. Neurol. 39, 683-691 (1980).
272. Eldon
G. Hill and Ralph T. Holman. Effect of
Dietary Protein Level upon Essential Fatty Acid (EFA) Deficiency. J. Nutr. 110,
1057-1060 (1980).
273. Elizabeth
S. Swanson, William P. Cunningham and Ralph T. Holman. Ultrastructure of
Glandular Ovarian Trichomes of Cypripedium
calceolus and C. reginae
(Orchidaceae). Am. J. Bot. 67, 784-789 (1980).
274. Ralph
T. Holman. Essential Fatty Acid
Deficiency. In "Total Parenteral
Nutrition," Proc. of the Symposium on Total Parenteral Nutrition sponsored
by the Food Science Committee, Council on Foods and Nutrition of the Am. Med.
Assoc., Nashville, TN, 1972, Eds. Philip L. White and Margarita E. Nagy,
Publishing Sciences Group, Inc., Acton, MA, pp. 214-220 (1974).
275. Bengt
A. Andersson, Ralph T. Holman, Lennart Lundgren and Gunnar Stenhagen. Capillary Gas Chromatograms of Leaf
Volatiles. A Possible Aid to Breeders
for Pest and Disease Resistance. J. Agr.
Food Chem. 28, 985-989 (1980).
276. M. M.
Mahfouz, A. J. Valicenti and R. T. Holman.
Desaturation of Isomeric trans-Octadecenoic
Acids by Rat Liver Microsomes. Biochim.
Biophys. Acta
618, 1-12 (1980).
277. Kensuke
Kameda, A. J. Valicenti and Ralph T. Holman.
Chain Elongation of trans-Octadecenoic
Acid Isomers in Rat Liver Microsomes.
Biochim. Biophys. Acta 618, 13-17 (1980).
278. M. M.
Mahfouz, S. Johnson and R. T. Holman.
The Effect of Isomeric trans-18:1
Acids on the Desaturation of Palmitic, Linoleic and Eicosa-8,11,14-trienoic
Acids by Rat Liver Microsomes. Lipids 15, 100-107 (1980).
279. Paul L.
Ogburn, Jr., Susan B. Johnson, Preston P. Williams and Ralph T. Holman. Levels
of Free Fatty Acids and Arachidonic Acid in Pregnancy and Labor. J. Lab. Clin. Med. 95, 943-949 (1980).
280. John
D. Lloyd-Still, Susan B. Johnson and Ralph T. Holman. Essential Fatty Acid Status in Cystic Fibrosis and the
Effects of Safflower Oil
Supplementation. Am. J. Clin.
Nutr. 34, 1-7 (1981).
281. M.
Mahfouz and R. T. Holman. Desaturation
of Isomeric cis 18:1 Acids. Lipids 15,
63-65 (1980).
282. Ralph
T. Holman. Answers to Questions Never
Really Asked. University of Minnesota
Annual Report, pp. 24-26 (1979).
283. Ralph
A. Nelson, Diane M. Huse, Ralph T. Holman, Barbara O. Kimbrough, Heinz W.
Wahner, C. Wayne Callaway and Aldine B. Hayles.
Nutrition, Metabolism, Body Composition and Response to the Ketogenic
Diet in Prader-Willi Syndrome. In
"The Prader Willi Syndrome," Chapter 8, Eds. V. A. Holm and P. L.
Pipes, University Park Press, Baltimore, MD, pp. 105-120 (1981).
284. Jeffrey
K. Yao, Ralph T. Holman, Michael F. Lubozynski and Peter James Dyck. Changes in Fatty Acid Composition of
Peripheral Nerve Myelin in Essential Fatty Acid Deficiency. Arch. Biochem. Biophys. 204, 175-180 (1980).
285. M.
Mahfouz, S. Johnson and R. T. Holman.
Inhibition of Desaturation of Palmitic, Linoleic and
Eicosa-8,11,14-trienoic Acids In Vitro by Isomeric cis-Octadecenoic Acids.
Biochim. Biophys. Acta 663, 58-68
(1981).
286. R. T.
Holman. New Challenges for Lipids. J. Am. Oil Chem. Soc. 57, 30A (1980).
287. Ralph
T. Holman, Susan B. Johnson, Osvaldo Mercuri, Herminia J. Itarte, Maria A.
Rodrigo and Maria E. De Tomas. Essential
Fatty Acid Deficiency in Malnourished Children.
Am. J. Clin. Nutr. 34, 1534-1539
(1981).
288. R. T.
Holman and M. M. Mahfouz. Cis- and trans-Octadecenoic
Acids as Precursors of Polyunsaturated Acids.
Prog. Lipid Res. 20, 151-156 (1981).
289. Ralph
T. Holman and Susan Johnson. Changes in
Essential Fatty Acid Profile of Serum Phospholipids in Human Disease. Prog. Lipid Res. 20, 67-73 (1981).
290. Ralph
T. Holman. Effect of Dietary Trans Fatty Acids Upon Prostaglandin
Precursors. In "Nutritional
Factors: Modulating Effects on Metabolic Processes," Miles Symposium
Series, No. 13, Ed. R. F. Beers, Jr. and E. G. Bassett, Raven Press, NY, pp. 523-537
(1981).
291. A. J.
Valicenti, F. J. Pusch and R. T. Holman.
Synthesis of [1-14C]Labeled Isomers of cis-
and trans-Octadecenoic Acids and Synthesis
of Octadecynoic Acids. Prog. Lipid Res. 20, 763-767 (1981).
292. T.
Riisom and R. T. Holman. Incorporation
into Lipid Classes of Products from Microsomal Desaturation of Isomeric trans-Octadecenoic Acids. Lipids 16,
647-654 (1981).
293. Peter
James Dyck, Jeffrey K. Yao, Donald E. Knickerbocker, Ralph T. Holman, Manuel R.
Gomez, Alvin B. Hayles and Edward H. Lambert.
Multisystem Neuronal Degeneration, Hepatosplenomegaly and Adrenocortical
Deficiency Associated with Reduced Tissue Arachidonic Acid. Neurology 31,
925-934 (1981).
294. O.
Hernell, G. Holmgren, S. F. Jagell, S. B. Johnson and R. T. Holman. Suspected
Faulty Essential Fatty Acid Metabolism in Sjogren-Larsson Syndrome. Pediatr. Res. 16,
45-49 (1982).
295. Ralph
T. Holman. Polyunsaturated Fatty Acid
Profiles in Human Disease. In
"Current Topics in Nutrition and Disease, New Trends in Nutrition,
Lipid Research, and Cardiovascular
Diseases," Vol. 5, Eds. N. G. Bazan, R. Paoletti and J. M. Iacono, Alan R.
Liss, Inc., New York, pp. 25-42 (1981).
296. Ralph
T. Holman, Susan B. Johnson and Terry F. Hatch.
A Case of Human Linolenic Acid Deficiency Involving Neurological
Abnormalities. Am. J. Clin. Nutr. 35, 617-623 (1982).
297. Editor: Progress in the Chemistry of Fats and Other
Lipids, Pergamon Press, Vol. 15, 391 pages (1979).
298. Editor: Progress in the Chemistry of Fats and Other
Lipids, Pergamon Press, Vol. 16, 317 pages (1978).
299. Editor: Progress in Lipid Research, Pergamon Press,
Vol. 17, 427 pages (1980).
300. Tom
Riisom, Susan Johnson, Eldon G. Hill and Ralph T. Holman. Effects of Experimental Diabetes on the
Essential Fatty Acid-Deficient Rat. J.
Lab. Clin. Med. 98, 764-775 (1981).
301. Ralph
T. Holman, Henry W. Blackburn, W. Eugene Cornatzer, P. Vincent Hegarty and
James Zavoral. The Amount and Degree of
Unsaturation of Dietary Fat. Proceedings
of Symposium "Revised U.S. Dietary Goals:
Implication for the Nation's Health," held at Earle Brown
Continuation Center, University of Minnesota, St. Paul, MN, November 10, 1978,
pp. 10-17.
302. Larry
D. Lawson and Ralph T. Holman.
-Oxidation of the Geometric and Positional Isomers of Octadecenoic Acid
by Rat Heart and Liver Mitochondria.
Biochim. Biophys. Acta 665, 60-65 (1981).
303. Ralph
T. Holman, William P. Cunningham and Elizabeth S. Swanson. A Closer Look at the Glandular Hairs on the
Ovaries of Cypripediums. Am. Orchid
Soc. Bull. 50, 683-687 (1981).
304. Ralph
T. Holman, Susan B. Johnson, Jonathan M. Gerrard, S. Michael Mauer, Susan
Kupcho-Sandberg and David M. Brown.
Arachidonic Acid Deficiency in Streptozotocin-induced Diabetes. Proc. Natl. Acad. Sci. USA 80, 2375-2379 (1983).
305. Irma
G. Rieckehoff, Ralph T. Holman and G. O. Burr.
Polyethenoid Fatty Acid Metabolism.
Effect of Dietary Fat on Polyethenoid Fatty Acids of Rat Tissues
(reprinted as a Nutrition Classic).
Nutr. Rev. 38, 247-250 (1980).
306. R. T.
Holman. The Ratio of Trienoic:Tetraenoic
Acids in Tissue Lipids as a Measure of Essential Fatty Acid Requirement
(printed as a Citation Classic). Current
Contents 12, 18 (1981).
307. Ralph
T. Holman. Essential Fatty Acids in
Nutrition and Disease. Society of
Chemical Industry Oils and Fats Group International Lecture, 4/13/81. Chem. Ind. 704-709 (1981).
308. Editor: Progress in Lipid Research, Pergamon Press,
Oxford, Vol. 18, 239 pages (1981).
309. Editor: Progress in Lipid Research, Pergamon Press,
Oxford, Vol. 19, 240 pages (1982).
310. Eldon
G. Hill, Susan B. Johnson, Larry D. Lawson, M. M. Mahfouz and Ralph T.
Holman. Perturbation of the Metabolism
of Essential Fatty Acids by Dietary Partially Hydrogenated Vegetable Oil. Proc. Natl. Acad. Sci. USA 79,
953-957 (1982).
311. Paul
L. Ogburn, Jr., Harvey Sharp, John D. Lloyd-Still, Susan B. Johnson and Ralph
T. Holman. Abnormal Polyunsaturated
Fatty Acid Patterns of Serum Lipids in Reye's Syndrome. Proc. Natl. Acad. Sci. USA 79, 908-911 (1982).
312. Ralph
T. Holman and Susan B. Johnson.
Essential Fatty Acid Deficiencies in Man. In AOCS Monograph "Dietary Fats and
Health," Eds. E. G. Perkins and W. J. Visek, American Oil Chemists'
Society, Champaign, Illinois, pp. 247-266 (1983), and as the Hogan Memorial
Lecture, University of Missouri, 1982.
313. R. T.
Holman, M. M. Mahfouz, L. D. Lawson and E. G. Hill. Metabolic Effects of Isomeric Octadecenoic
Acids. In AOCS Monograph "Dietary
Fats and Health," Eds. E. G. Perkins and W. J. Visek, American Oil
Chemists' Society, Champaign, Illinois, pp. 320-340 (1983), and as the Hogan
Memorial Lecture, University of Missouri, 1982.
314. Ralph
T. Holman. Studies on the Fragrances of
North American Terrestrial Orchids. In
"North American Terrestrial Orchids Symposium II, Proceedings and Lecture,
October 1981," Ed. Elmer Plaxton, Michigan Orchid Society, Livonia, MI,
pp. 32-40 (1983).
315. Editor:
Progress in Lipid Research, Pergamon Press, Vol. 20, 911 pages (1981).
316. Ralph
T. Holman and Susan B. Johnson.
Linolenic Acid Deficiency in Man.
Nutr. Rev. 40, 144-147 (1982).
317. Larry
D. Lawson, Eldon G. Hill and Ralph T. Holman.
Accumulation and Depletion of trans-Octadecenoic
Acid in Rat Peripheral Nerve Phospholipid.
Biochim. Biophys. Acta 712, 117-122
(1982).
318. Ralph
T. Holman. Clinical Linolenic Acid
Deficiency. In "Nutrition and the
M.D.," Vol. 8, No. 10, p. 4 (1982).
319. Ralph
T. Holman. Fragrance in the Lives and
Identities of Orchids. In (a)
"Houston Happenings," Vol. 10, No. 5, pp. 2-3 (1982); (b) Orchidian,
issue 3, p. 62 (1982); (c) The Mid-American, pp. 5-6 (1983); (d) J. Orchid
Species Soc. Victoria, Vol. 2, #3, pp. 3-4, July 1983; (e) The Orchadian, J.
Austral. Native Orchid Soc., 7 No. 10, pp.
240-241 (1983).
320. Ralph
T. Holman, Susan B. Johnson and Terry F. Hatch.
Letter to the Editor: Reply to
the letter by Bozian and Moussavian. Am.
J. Clin. Nutr. 36, 1254-1255 (1982).
321. Ralph
T. Holman, Susan B. Johnson and Terry F. Hatch.
Letter to the Editor: Reply to
letter by H. C. Meng. Am. J. Clin. Nutr.
37, 159-160 (1983).
322. Jeffrey
K. Yao, Kevin P. Cannon, Ralph T. Holman and Peter James Dyck. Effects of Polyunsaturated Fatty Acid Diets
on Plasma Lipids of Patients with Adreno-Multineuronal Degeneration,
Heptasplenomegaly and Fatty Acid Derangement.
J. Neurol. Sci. 62 67-76 (1983).
323. Larry
D. Lawson, Eldon G. Hill and Ralph T. Holman.
Suppression of Arachidonic Acid in Lipids of Rat Tissues by Dietary
Mixed Isomeric cis and trans Octadecenoates. J.
Nutr. 113, 1827-1835 (1983).
324. R. T.
Holman and S. B. Johnson. The Effects of
Disease and Nutrition upon Metabolism of Polyunsaturated Fatty Acids. In "Fats for the Future," The
Proceedings of the International Conference on Oils, Fats and Waxes, Auckland
1983, Eds. S. G. Brooker, A. Renwick, S. F. Hannan and L. Eyres, Duromark
Publishing Co., Auckland, New Zealand, pp. 206-212 (1983).
325. A.
Valicenti, F. J. Pusch and R. T. Holman.
Synthesis of Octadecynoic Acids and [1-14C]Labeled Isomers of Octadecenoic
Acids. Lipids 20 234-242 (1985).
326. H. J.
Dutton, S. B. Johnson, W. H. Heimermann, F. J. Pusch, R. T. Holman and F. D.
Gunstone. Determination of Structure and
Composition of Mixed Octadecadienoic Acids via Ozonolysis, Gas Chromatography
and Computer Solution of Simultaneous Equations. Proceedings of the 16th ISF Congress,
Budapest, 1983. Edited by N. Hollo, 2 vol., pp. 61-77 (1985).
327. Paul
L. Ogburn, Preston P. Williams, Susan B. Johnson and Ralph T. Holman. Serum Arachidonic Acid Levels in Normal and
Preeclamptic Pregnancies. Am. J.
Obstetr. Gynecol. 148, 5-9 (1984).
328. Tim R.
Kramer, Mary Briske-Anderson, Susan B. Johnson and Ralph T. Holman. Influence
of Reduced Food Intake on Polyunsaturated Fatty Acid Metabolism in Zinc-Deficient
Rats. J. Nutr. 114, 1224-1230 (1984).
329. Tim R.
Kramer, Mary Briske-Anderson, Susan B. Johnson and Ralph T. Holman. Effects of Biotin Deficiency on
Polyunsaturated Fatty Acid Metabolism in Rats.
J. Nutr. 114, 2047-2052 (1984).
330. Larry
D. Lawson, Eldon G. Hill and Ralph T. Holman.
Dietary Fats Containing Concentrates of cis
or trans Octadecenoates and the Patterns of
Polyunsaturated Fatty Acids of Liver Phospholipids. Lipids 20,
262-267 (1985).
331. Ralph
T. Holman. Influence of Hydrogenated
Fats on the Metabolism of Polyunsaturated Fatty Acids. In "The Role of Fats in Human
Nutrition," Edited by F. B Padley, J. Podmore, J. P. Brun, R. Burt and B.
W. Nichols, Society of Chemical Industry, London, England, pp. 48-61 (1985).
332. Ralph T.
Holman, Paul L. Ogburn, Jr. and Susan B. Johnson. Nonesterified Fatty Acids as Toxins
Contributing to the Pathogenesis of Reye's Syndrome and Other Microvesicular Lipid Hepatic
Diseases. In "Reye's Syndrome IV,
Proceedings of the 4th International Conference on Reye's Syndrome" edited
by J. Dennis Pollack, National Reye's Syndrome Foundation, Bryan, OH, pp.
163-189 (1985).
333. Eric
Hagsater and Ralph T. Holman. Epidendrum durangense, A New Species from
Western Mexico. Orquidea (Mex.) 9(2), 299-312 (1984).
334. Patrick
Kemp, David J. Lander and R. T. Holman.
The Hydrogenation of the Series of Methylene-Interrupted cis,cis-Octadecadienoic Acids by Pure Cultures
of Six Rumen Bacteria. Br. J. Nutr. 52, 171-177 (1984).
335. Ralph
T. Holman. Control of Polyunsaturated
Acids in Tissue Lipids. J. Am. College Nutr. 5,
236-265 (1986).
336. Susan
B. Johnson, Ellen Gordon, Craig McClain, Graeme Low and Ralph T. Holman. Abnormal Polyunsaturated Fatty Acid Patterns
of Serum Lipids in Alcoholism and Cirrhosis:
Arachidonic Acid Deficiency in Cirrhosis. Proc. Natl. Acad. Sci. 82, 1815-1818 (1985).
337. Donald
M. Mock, David L. Baswell, Herman Baker, Ralph T. Holman and Lawrence
Sweetman. Biotin Deficiency Complicating
Parenteral Alimentation: Diagnosis, Metabolic
Repercussions, and Treatment. J.
Pediatr. 106, 762-769 (1985).
338. Donald
M. Mock, David L. Baswell, Herman Baker, Ralph T. Holman and Lawrence
Sweetman. Biotin Deficiency Complicating
Parenteral Alimentation: Diagnosis,
Metabolic Repercussions, and Treatment.
N. Y. Acad. Sci., 447, 314-334
(1985).
339. Tim R.
Kramer, Mary Briske-Anderson, Susan B. Johnson and Ralph T. Holman. Polyunsaturated Fatty Acid Patterns in
Lymphoid and Nonlymphoid Tissues of Zinc Deficient and Pair-Fed Rats. Nutr. Res. 6,
1063-1064 (1986).
340. T. R.
Kramer, M. Briske-Anderson, S. B. Johnson and R. T. Holman. Reply to the Letter by Drs. Cunnane and
Horrobin. J. Nutr. 115, 502-503 (1985).
341. Ralph
T. Holman and Armand B. Christophe.
Human Essential Fatty Acid Deficiencies of Dietary and Metabolic
Origin. In "Clinical Studies in
Medical Biochemistry," Eds. Robert H. Glew and Stephen P. Peters, Oxford
University Press, New York, pp. 215-224 (1987).
342. Ralph
T. Holman. Nutritional and Biochemical
Evidences of Acyl Interaction with Respect to Essential Polyunsaturated Fatty
Acids. Prog. Lipid Res. 25, 29-39 (1986).
343. Alan
R. Sinaiko, Ralph T. Holman and Thomas P. Green. Effectiveness of Dietary Essential Fatty Acid
Deficiency in Development of a Model of Endogenous Renal Prostaglandin
Deficiency. Prostaglandins Leukotrienes
Med. 19, 87-98 (1985).
344. P. L.
Ogburn, Jr., S. I. Turner, P. P. Williams, S. B. Johnson and R. T. Holman. Preeclampsia and Essential Fatty Acid
Patterns. Prog. Lipid Res. 25, 417-419 (1986).
345. Paul
L. Ogburn, Jr., Preston P. Williams, Susan B. Johnson and Ralph T. Holman. Letter to the Editor "Response to Drs.
Rosing and Olund." Am. J. Obstet.
Gynecol. 153, 714 (1985).
346. Editor,
Progress in Lipid Research, Pergamon Press, Vol. 21, 336 pages (1982).
347. Editor,
Progress in Lipid Research, Pergamon Press, Vol. 22, 299 pages (1983).
348. Editor,
Progress in Lipid Research, Pergamon Press, Vol. 23, 246 pages (1985).
349. Ralph
T. Holman. Essential Fatty Acids and
Nutritional Disorders. In "Lipids
in Modern Nutrition," Eds. M. Horisberger and U. Bracco, Nestle'
Nutrition, Vevey, Switzerland, and Raven Press, New York, pp. 157-171 (1987).
350. Victor
G. Soukup and Ralph T. Holman. Fatty
Acids of North American Pedicellate Trillium Seed. Phytochemistry 26,
1015-1018 (1987).
351. Ralph
T. Holman. Nutritional and Functional
Requirements for Essential Fatty Acids.
In "Dietary Fat and Cancer," Eds. Clement Ip, D. F. Birt, A.
E. Rogers and C. Mettlin, Alan R. Liss Publishers, New York, pp. 211-228
(1986).
352. T. R.
Kramer, M. Briske-Anderson, S. B. Johnson and R. T. Holman. Influences of Dietary Polyunsaturated or
Saturated Fats and of Concanavalin-A upon Proliferation of Spleen Lymphoid
Cells from Rats. Nutr. Res. 6, 1219-1227 (1986).
353. R.T.
Holman, C.E. Adams, R.A. Nelson, S.J.E. Grater, J.A. Jaskiewicz, S.B. Johnson
and J.W. Erdman, Jr. Patients with
Anorexia Nervosa Demonstrate Deficiencies of Selected Essential Fatty Acids,
Compensatory Changes in Non-essential Fatty Acids and Decreased Fluidity of
Plasma Lipids. J. Nutr. 125, 901-907
(1995)
354. R. T. Holman. Conditions Influencing Essentiality of
Polyunsaturated Acids. In:
"Proceedings of the NATO Advanced Research Workshop on Advanced Technologies and their Nutritional
Implications in the Production of Edible Fats," Held March 17-21, 1986 in
Selvino, Italy, Eds. C. Galli and E. Fedeli, Plenum Press, NY and London, pp.
1-12 (1987).
355. W. W.
Christie, E. Y. Brechany, S. B. Johnson and R. T. Holman. A Comparison of Pyrrolidide and Picolinyl
Ester Derivatives for Identification of Fatty Acids in Natural Samples by Gas
Chromatography-Mass Spectrometry. Lipids
21, 657-661 (1986).
356. H. L.
Sharp, J. A. Lindahl, D. K. Freese, B. Burke, D. Johnson, S. B. Johnson and R.
T. Holman. A New Hepato-Pancreato-Renal
Disorder Resembling Tyrosinemia Involving Neuropathy and Abnormal Metabolism of
Polyunsaturated Acids. J. Pediatr. Gastroenterol.
Nutr. 7, 167-176 (1988).
357. P.
Alden, B. Svingen, S. Johnson, F. Konstantinides, R. T. Holman and F. B.
Cerra. Partial Correction of Exogenous
Lipid of Abnormal Patterns of Polyunsaturated Fatty Acids in Plasma
Phospholipids of Stressed and Septic Surgical Patients. Surgery 100,
671-678 (1986).
358. R. T.
Holman. Showy Lady's Slipper (grown and
photographed by Holman), a 4 color
18" x 24" print (poster) of a triplet Minnesota's State flower to be given to contributors to Hormel
Institute research on orchids, 2000 copies
printed in 1985.
359. B.A.
Svingen, M.J. Murray, T.L. Yaksh and R. T. Holman. Plasma Arachidonate and Lung Surfactant
Composition in Unanesthetized Canine Endotoxin Shock. Circulatory Shock ?????
360. A.
Christophe, E. G. Hill and R. T. Holman.
Efficacy of Linoleic Acid Administered Rectally as Monoglyceride. Lipids 22,
328-332 (1987).
361. P. B.
Alden, B. Svingen, C. Deutschman, S. B. Johnson, F. N. Konstantinides, R. T.
Holman and F. B. Cerra. Essential Fatty
Acid Status in Isolated Closed Head Injury.
J. Trauma 27 (9), 1039-1043 (1987).
362. R. T.
Holman, Ebbholmen. A Centennial Edition of Our Family
Chronicle. Privately published. Libr.
Congr. #TXu 246 877, pp. 450 (1986).
363. J. W.
Crofts, P. L. Ogburn, S. B. Johnson and R. T. Holman. Polyunsaturated Fatty Acids of Serum Lipids
in Myocardial Infarction. Lipids 23, 539-545 (1988).
364. Editor,
Progress in Lipid Research, Pergamon Press, Vol. 24, 346 pages (1986).
365. P. L.
Ogburn, S. I. Turner, P. P. Williams, S. B. Johnson and R. T. Holman. Essential Fatty Acid Patterns in
Preeclampsia. Zentalblatt Gynakal 108, 983-989 (1986).
366. H. J.
Dutton, S. B. Johnson, F. J. Pusch, R. T. Holman, M. S. F. Lie Ken Jie and F.
D. Gunstone. Composition of Mixed
Octadecadienoates via Ozonolysis Chromatography and Computer Solutions of
Linear Equations. Lipids 23, 481-489 (1988).
367. W. W.
Christie, E. Y. Brechany, F. D. Gunstone, M. Lie Ken Jie and R. T. Holman. Mass
Spectra of the Picolynyl Ester Derivatives of Some Non-Methylene-Interrupted
Octadecadienoates. Lipids 22, 664-666 (1987).
368. D. M.
Mock, S. B. Johnson and R. T. Holman.
Effects of Biotin Deficiency on Serum Fatty Acid Composition: Evidence for Abnormalities in Humans. J. Nutr. 118,
342-348 (1988).
369. D. M.
Mock, N. I. Mock, S. B. Johnson and R. T. Holman. Effects of Biotin Deficiency on Plasma and Tissue Fatty Acid
Composition: Evidence for Abnormalities
Rats. Pediatr. Res. 24, 396-403 (1988).
370. A. M.
Kools, J. G. Straka, H. D. Hill, D. I. Whitmer, R. T. Holman and J. R.
Bloomer. Modulation of Hepatic
Ferrochelatase Activity by Dietary Manipulation of Mitochondrial Phospholipid
Fatty Acyl Groups. Hepatology 9, 557-561 (1989).
371. J. D.
Lloyd-Still, S. B. Johnson and R. T. Holman.
Essential Fatty Acid Status and Fluidity of Plasma Phospholipids in
Cystic Fibrosis Infants. Am. J. Clin.
Nutr. 54, 1029-1035 (1991).
372. I. I.
Rusoff, R. T. Holman and G. O. Burr.
Spectroscopic Data in Fats, Fatty
Acids and Their Esters. Soap,
Perfumery Cosmet. Yr. Book 1965, 53-57.
373. R. T. Holman. George O. Burr and the Discovery of Essential
Fatty Acids. J. Nutr. 118, 535-540 (1988).
374. R. T.
Holman. A Brief History of
"Progress in Lipid Research".
Prog. Lipid Res. 27, 1-4 (1988).
375. S. D.
Phinney, R. S. Odin, S. B. Johnson and R. T. Holman. Reduced Arachidonate in Serum Phospholipids and Cholesteryl Esters
associated with Vegetarian Diets in Humans.
Am. J. Clin. Nutr. 51, 385-392
(1990).
376. F. B.
Cerra, P. B. Alden, F. Negro, T. Billiar, B. A. Svingen, J. Licari, S. B. Johnson
and R. T. Holman. Sepsis and Exogenous
Lipid Modulation. J. Parenter. Enterol.
Nutr. 12, 63S-68S (1988).
377. S. B.
Johnson, T. R. Kramer, M. Briske-Anderson and R. T. Holman. Fatty Acid Pattern of Tissue Phospholipids in
Copper and Iron Deficiencies. Lipids 24, 141-145 (1989).
378. Editor,
Progress in Lipid Research, Pergamon Press, Vol. 25, 693 pages (1986).
379. Editor,
Progress in Lipid Research, Pergamon Press, Vol. 26, 348 pages (1987).
380. R. T.
Holman. Upsala Community Covenant
Church. A Swedish Pioneer Church
1888-1988. Privately published, Libr.
Congr. #TXu 304 974, pp. 143 (1987).
381. T. R.
Billiar, P. E. Bankey, B. A. Svingen, R. D. Curran, M. A. West, R. T. Holman,
R. L. Simmons and F. B. Cerra. Fatty
Acid Intake and Kupffer Cell Function:
Fish Oil Alters Eicosanoid and Monokine Production to Endotoxin
Stimulation. Surgery 104, 343-349 (1988).
382. S.D.
Phinney, P.G. Davis, S.B. Johnson, and R. T. Holman. Obesity and Weight Loss Alter Serum
Polyunsaturated Lipids in Humans. Am. J.
Clin. Nutr. 53, 831-838 (1991).
383. S.D.
Phinney, S.B. Johnson, R.T. Holman, A.M. Reisenauer, and C.H. Halsted. Chronic Ethanol Ingestion Selectively Impairs
Essential Fatty Acid Desaturation in the Miniature Pig. Submitted to Alcoholism.
384. R.T.
Holman. James Franklyn Mead October 24,
1916 to November 30, 1987. Lipids 24, 166 (1989).
385. R.T.
Holman, S.B. Johnson and Emre Kokmen.
Deficiencies of Polyunsaturated Fatty Acids and Replacement by
Non-essential Fatty Acids in Plasma Lipids in Multiple Sclerosis. Proc. Natl. Acad. Sci. USA 86, 4720-4724 (1989).
386.
387. R.G.
Knodell, D.I. Whitmer, and R.T. Holman.
Influence of Hyperalimentation on Rat Hepatic Microsomal Fluidity and
Function. Gastroenterology 98, 1320-1325 (1990).
388. E.S.
Kang, S.B. Johnson, and R.T. Holman.
Fatty Acid Composition of Hepatic Triglycerides from Reye's
Syndrome: Implications for Hepatic
Desaturase Abnormalities. Clin. Chim.
Acta 204, 167-178 (1991).
389. R.T.
Holman. Highpoints in an Affair with Polyunsaturated
Acids. In "Health Effects of w3 Polyunsataturated Fatty
Acids in Seafoods", World Review of Nutritionand Dietetics, Vol. 66 (A.P.
Simopoulos, Series Ed.) (A.P. Simopoulos, R. R. Kifer, R. E. Martin and J. M.
Barlow, Volume Eds.) Karger, Basel, pp. 4-8 (1991)
390. S.
Pullman-Mooar, M. Laposata, D. Lem, R.T. Holman, L.J. Leventhal, D. De Marco,
and R.B. Zurier. Alteration of the
Cellular Fatty Acid Profile and the Production of Eicosanoids in Human
Monocytes by Gamma-Linolenic Acid.
Arthritis Rheum. 33, 1526-1533
(1990).
391. S.D.
Phinney, P.G. Davis, S.B. Johnson, and R.T. Holman. Obesity and Weight Loss Alter Serum
Polyunsaturated Fatty Acid Metabolism in Humans. Am. J. Clin. Nutr. 53, 831-838 (1991).
392. S.D.
Phinney, A.B. Tang, S.B. Johnson, and R.T. Holman. Reduced Adipose 18:3w3 with Weight Loss by Very
Low Caloric Dieting. Lipids 25, 798-806 (1990).
393. F.B.
Cerra, S. Lehmann, N. Konstantinides, F. Konstantinides, E.P. Shronts, and R.T.
Holman. Effect of Enteral Nutrient on in
vitro Tests of Immune Function in ICU Patients:
A Preliminary Report. Nutrition 6, 84-87 (1990).
394. R.T.
Holman. Control of Polyunsaturated Acids
in Tissue Lipids. In "Oil and Fat
in Nutrition and Disease" (Ichiro Hara, Hiroyuki Shimasaki, Yoshiaki
Machida, Eds.) Saiwai Shobo Company, Japan, pp. 2-42 (1990) Translated to Japanese 1990
395. J.S.
Crockett, M. Gross, W.W. Christie, and R.T. Holman. Collisional Activation of a Series of
Homoconjugated Octadecadienoic Acids with Fast Atom Bombardment and Tandem Mass
Spectrometry. J. Am. Soc. Mass Spectrom.
1, 183-191 (1990).
396. R.T.
Holman, F. Pusch, B. Svingen, and H.J. Dutton.
Unusual Isomeric Polyunsaturated Fatty Acids in Liver Phospholipids in
Rats Fed Hydrogenated Oil. Proc. Natl.
Acad. Sci. USA 88, 4830-4834 (1991).
397. F.B.
Cerra, R.T. Holman, P.E. Bankey, J.E. Mazuski, and J.J. LiCari. w3 Polyunsaturated Fatty Acids as Modulators
of Cellular Function in the Critically Ill.
Pharmacotherapy 11(1), 71-76 (1991).
398. M.J.
Murray, B.A. Svingen, R.T. Holman, and T.L. Yaksh. The Effects of Fish Oil Diet on Pigs'
Cardiopulmonary Response to Bacteremia.
J. Parent. Enteral. Nutr. 15,
152-158 (1991).
399. R.T.
Holman. Hugh MacDonald Sinclair: Advocate of the Essential Fatty Acids. In "Health Effects of w3
Polyunsaturataed Fatty Acids in Seafoods", World Review of Nutrition and
Dietetics, Vol. 66 (A.P. Simopoulos, Series Ed.) (A.P. Simopoulos, R.R. Kifer,
R.E. Martin, and J.M. Barlow, Volume Eds) Karger, Basel, pp. XX-XXIV
(Dedication) (1991).
400. M.J.
Murray, B.A. Svingen, T.L. Yaksh, and R.T. Holman. Effects of Endotoxin on Pigs Prefed w-3 vs w-6 Fatty Acid-Enriched
Diets. Am. J. Physiol. 265, E920-E927 (1993).
401. B.M.
Myers, F.G. Prendergast, R.T. Holman, S.M. Kuntz, and N.F. La Russo. Alterations in the Structure, Physicochemical
Properties and pH of Hepatocyte Liposomes in Experimental Iron Overload. J. Clin. Invest. 88, 1207-1215 (1991).
402. R.T.
Holman, S.B. Johnson, and P.L. Ogburn.
Deficiency of Essential Fatty Acids and Membrane Fluidity During
Pregnancy and Lactation. Proc. Natl.
Acad. Sci. USA 88, 4835-4839 (1991).
403. A.B.
Christophe, and R.T. Holman. Diet and
EFA Status in Cystic Fibrosis Patients.
INFORM 3, 449-455 (1992).
404. F.B.
Cerra, R.T. Holman, P.E. Bankey, and J.E. Mazuski. Nutritional Pharmacology: Its Role in the Hypermetabolism-Organ Failure
Syndrome. Critical Care Medicine 18, S154-S158 (1990).
405. P.E.
Bankey, T.R. Billiar, W.Y. Yeng, A. Carlson, R.T. Holman, and F.B. Cerra. Modulation of Kupffer cell membrane
phospholipid function by n-3 polyunsaturated fatty acids. J. Surg. Res. 46,
439-444 (1989).
406. F.B.
Cerra, S. Lehmann, N. Konstantinides, J. Dzik, J. Fish, F. Konstantinides, J.J.
LiCari, and R.T. Holman. Improvement in
Immune Function in ICU Patients by Enteral Nutrition Supplemented with
Arginine, RNA, and Menhaden Oil is Independent of Nitrogen Balance. Nutrition 7,
193-199 (1991).
407. D.
Spielmann, H. Traitler, G. Crozier, M. Fleith, U. Bracco, P.A. Finot, M.
Berger, and R.T. Holman. Biochemical and
Bioclinical Aspects of Blackcurrant Seed Oil w3 and w6 Balanced Oil. In "Dietary w3 and w6 Fatty Acids (G. Galli and
A. P. Simopoulos, Eds.) Plenum Publishing Corp., pp. 309-321 (1989).
408. R.T.
Holman, S.B. Johnson, D. Bibus, D.C. Spencer, and J.V. Donadio, Jr. Essential Fatty Acid Deficiency Profiles in
Idiopathic Immunoglobulin A Nephropathy.
Am. J. Kidney Dis. 23, 648-654
(1994).
409. R.T.
Holman, and H.J. Dutton. Essential Fatty
Acid Deficient Rats Fed Hydrogenated Oil - A Response. Lipids 27,
486 (1992).
410. W.W.
Christie, E.Y. Brechany, and R.T. Holman.
Mass Spectra of the Picolinyl Esters of Isomeric Mono- and Dienoic Fatty
Acids. Lipids 22, 224-228 (1987).
411. T.
Zhang, M.J. Murray, K. Klocke, J.M. Miles, and R.T. Holman. The Effects of the Incubation of Long-Chain
Polyunsaturated Fatty Acids on Platelet Lipids and Thromboxane Release. Submitted to J. Lipid Res. 4/29/93. Being revised for a different journal - per
Murray's secretary 5/16/94.
412. R.T.
Holman. A Long Scaly Tale - The Study of
Essential Fatty Acid Deficiency at the University of Minnesota. In "Essential Fatty Acids and
Eicosanoids" (Andrew Sinclair and Robert Gibson, Eds.) American Oil
Chemists' Society, Champaign, IL, pp. 3-17 (1993).
413. S.D.
Phinney, J.S. Stern, K.E. Burke, A.B. Tang, G. Miller, and R.T. Holman. Human Subcutaneous Adipose Tissue Shows
Site-Specific Differences in Polyunsaturated Fatty Acid Composition. Am. J.
Clin. Nutr. 60; 725-729 (1994)
414. D.
Lax, R.T. Holman, S.B. Johnson, S.L. Zang, Y. Li, G.R. Noren, N.A. Staley, and
S. Einzig. Myocardial Lipid Composition
in Turkeys with Dilated Cardiomyopathy.
Cardiovascular Res. 28, 407-413
(1994).
415. B.M.
Myers, F.G. Prendergast, R.T. Holman, S.M. Kuntz and N.F. LaRusso. Alterations in Hepatocyte Lysosomes in
Experimental Hepatic Copper Overload in Rats.
Gasteroenterology 105, 1814-1823
(1993).
416. R.T.
Holman. A Brief History of PROGRESS IN
LIPID RESEARCH. In "Robert Maxwell
& Pergamon Press" (E. Maxwell, Ed), Pergamon Press, New York, NY,
pp.305-308 (1988).
417. R.T.
Holman, D.M. Bibus, G.H. Jeffrey, P. Smethurst and J.W. Crofts. Abnormal Plasma Lipids of Patients with Retinitis Pigmentosa. Lipids 29,
61-65 (1994).
418. R.T.
Holman. Omega 3 Deficiencies in
Humans. In "Proceedings of the 55th
Flax Institute of the United States" (J.F. Carta, Ed.) pp. 4-11 (1994).
419. A.J.
Sinclair, L. Johnson, K. O'Dea and R.T. Holman.
Diets Rich in Lean Beef Increase Arachidonic Acid and Long-Chain w3
Polyunsaturated Fatty Acid Levels in Plasma Phospholipids. Lipids 29,
337-343 (1994).
420. A.B.
Christophe, W.J. Warwick and R.T. Holman.
Serum Fatty Acid Profiles in Cystic fibrosis patients and their
parents. Lipids 29, 569-575 (1994).
421. R.T.
Holman, C.E. Adams, R.A. Nelson, S.J.E. Grater, J.A. Jaskiewicz, S.B. Johnson
and J.W. Erdman, Jr. Patients with
Anorexia Nervosa Demonstrate Deficiencies of Selected Essential Fatty Acids,
Compensatory Changes in Nonessential Fatty Acids and Decreased Fluidity of
Plasma Lipids. J. Nutr. 125, 901-907 (1995).
422. S.D.
Phinney, J.S. Stern, K.E. Burke, A.B. Tang, G. Miller and R.T. Holman. Human Subcutaneous Adipose Tissue Shows
Site-Specific Differences in Fatty Acid Composition. Am. J. Nutr. 60,
725-729 (1994).
423. P.S.
Tietz, R.T. Holman, L.J. Miller and N.F. LaRusso. Isolation and Characterization of Rat
Cholangiocyte Vesicles Enriched in Apical or Basolateral Plasma Membrane
Domains. Biochemistry 34, 15436-15443 (1995).
424. T.
Zhang, M.J. Murray, K. Klocke, J.M. Miles and R.T. Holman. The Effects of the Incubation of Long-Chain
Polyunsaturated Fatty Acids on Platelet Lipids and Thromboxane Release. Submitted to Prost. Leuk. Ess. Fatty Acids.
12/27/95.
425. R.T.
Holman. How I Became a Lipid Chemist 50
Years Ago. INFORM 7: 402-408 (1996)
426. R.T.
Holman. Fifty Years Ago - How I Got My
Start In Lipids, and Where It Led Me. FASEB J. 10, 931-934 (1996)
427. R. T.
Holman. Omega 3 and Omega 6 Essential
Fatty Acid Status in Human Health and Disease.
in “Fatty Acids and Behavior”, eds S. Yehuda and D. Mostofsky. Humana Press, Totowa, N.J. pp 000-000
Nov. 1996
428. R. T.
Holman. Deficiencies of Essential Omega
3 Fatty Acids in Humans Are Not Rare.
Proc. of the 56th Flax Institute of the United States , Fargo, N.D. pp. 1-8 (1996)
429. J.
Lloyd-Still, D. Bibus, O. Powers, S.
Johnson and R.T. Holman. Essential
Fatty Acid Deficiency and Predisposition
to Lung Disease in Cystic Fibrosis.
subm. Acta Paediatrica 1996
430. Ralph T.
Holman, S.B. Johnson, D. M. Bibus, T.C. Okeahiaalem and Peter O. Egwim.
High Omega 3 EFA Status in Nigerians and Low Status
in Minnesotans. Submitted to
W. W. W. J. Biol Sept. 1996
431.
Robert B. Zurier, Douglas M.
Bibus and Ralph T. Holman. Deficiencies
of Polyunsaturated Fatty Acids and Replacement by Nonessential Fatty Acids in
Plasma Lipids of Rheumatoid Arthritis Patients.
Submittet to Lipids 18oct96
432. Ralph T.
Holman, N.L.Parinandi, Eva Deli, Douglas
Bibus, R. Kaleysa Raj and T. Ramasarma.
High w3 Nutritive Status Indicated by Essential Fatty Acid Profiles in
Keralites of India. Manuscript in
preparation.
